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Effects of Upper Cervical Manual Therapy on Obliquus Capitis Inferior Muscle Morphology

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Study Aim

This study aims to evaluate the effects of upper cervical manual therapy on the morphology of your Obliquus Capitis Inferior muscle, specifically measuring changes in its length and width using musculoskeletal ultrasound.

What is being tested

Single Thrust for Neck Joint Adjustment

+ Single Thrust for Neck Joint Adjustment

Other
Who is being recruted

Neurologic Manifestations+2

+ Pain

+ Signs and Symptoms

From 18 to 65 Years
+5 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: May 2025
See protocol details

Summary

Principal SponsorFlorida Gulf Coast University
Study ContactRob Sillevis, PhDMore contacts
Last updated: July 24, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: May 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on understanding the immediate impacts of two different upper neck manual therapy techniques. It involves individuals receiving these therapies and examines specific aspects related to neck posture and muscle health. The research aims to improve understanding of how these therapies affect the Obliquus Capitis Inferior, a muscle located at the base of the skull, which is often associated with neck pain and discomfort. The findings could potentially enhance treatment strategies for conditions related to neck pain and posture. During the study, participants receive one of the two manual therapies. The effects of these therapies are then measured using musculoskeletal ultrasound, a safe and non-invasive imaging technique. This technique helps assess changes in the length and width of the Obliquus Capitis Inferior muscle. The study also evaluates the craniovertebral angle, a measure of neck posture, and the perceived position of the atlas, the topmost vertebra of the spine.

Principal SponsorFlorida Gulf Coast University
Study ContactRob Sillevis, PhDMore contacts
Last updated: July 24, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

80 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Neurologic ManifestationsPainSigns and SymptomsPathological Conditions, Signs and SymptomsHeadache

Criteria

3 inclusion criteria required to participate
no contraindications to cervical manual therapy

no previous history of cervical spine surgery or traumatic cervical injury

read and understand English

2 exclusion criteria prevent from participating
any absolute contraindications to cervical manipulation

any other medical condition considered unsafe for manual therapy

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
Participants in this group receive a single long axis thrust manipulation on the C1-C2 vertebrae. This involves a brief, controlled force applied in a specific direction to the neck.

Group II

Sham
Participants receive a gentle stretching technique focused on the first three neck vertebrae (C1-C3). This involves a 5-second hold, repeated three times.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Florida Gulf Coast University Marieb Hall 101

Fort Myers, United StatesOpen Florida Gulf Coast University Marieb Hall 101 in Google Maps
Recruiting
One Study Center