Recruiting

Relationship Between Pain Catastrophizing and Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy Patients

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Study Aim

This observational study aims to explore the connection between your preoperative Pain Catastrophizing Scale scores and the occurrence of postoperative nausea and vomiting (PONV) after a laparoscopic cholecystectomy procedure.

What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Nausea+7

+ Neurologic Manifestations

+ Pathologic Processes

From 18 to 65 Years
+16 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: January 2026
See protocol details

Summary

Principal SponsorTrabzon Kanuni Education and Research Hospital
Study Contactsedanur sulaMore contacts
Last updated: July 17, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 15, 2026

Actual date on which the first participant was enrolled.

This study is designed as a prospective, cross-sectional, and observational study. The Pain Catastrophizing Scale (PCS) is a well-established self-report instrument developed to assess catastrophic thinking related to pain. It evaluates how individuals perceive and respond to pain, focusing on tendencies such as rumination, magnification, and feelings of helplessness. Evidence suggests that PCS is a strong predictor of pain intensity, independent of anxiety levels. In this study, the validated Turkish version of the Pain Catastrophizing Scale will be used. Postoperative nausea, vomiting, and retching are common adverse events that can complicate recovery from anesthesia. Patients often perceive these symptoms as more distressing than postoperative pain, and they represent important outcomes affecting patient satisfaction and recovery. The present study aims to investigate the relationship between pain perception during intravenous (IV) cannulation, pain catastrophizing levels, and postoperative nausea and vomiting. By evaluating numeric pain scores during IV access alongside PCS scores, this study seeks to explore whether preoperative pain perception and psychological factors are associated with the frequency of postoperative nausea and vomiting. The findings of this study are expected to contribute to a better understanding of the role of psychological factors in postoperative symptoms and may help improve anesthesia practices by supporting more individualized, patient-centered perioperative care.

Principal SponsorTrabzon Kanuni Education and Research Hospital
Study Contactsedanur sulaMore contacts
Last updated: July 17, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

64 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

NauseaNeurologic ManifestationsPathologic ProcessesPostoperative ComplicationsSigns and SymptomsSigns and Symptoms, DigestivePathological Conditions, Signs and SymptomsVomitingPainPostoperative Nausea and Vomiting

Criteria

4 inclusion criteria required to participate
Able to provide informed consent

American Society of Anesthesiologists (ASA) physical status I-II-III

Adult patients aged 18-65 years

Scheduled for elective laparoscopic cholecystectomy

12 exclusion criteria prevent from participating
Psychiatric disorders

Pregnancy

History of cerebrovascular disease (stroke)

Chronic renal disease

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Trabzon Kanuni Education and Research Hospital

Trabzon, Turkey (Türkiye)Open Trabzon Kanuni Education and Research Hospital in Google Maps
Recruiting
One Study Center