Recruiting

COMETCOMET Study: Assessing Professional, Personal and Psychological Trajectories of General Internal Medicine Residents

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Study Aim

This study aims to observe the changes in psychological distress, professional fulfillment, burnout, and depressive symptoms among general internal medicine residents, as well as the percentage of participants who continue in general internal medicine training or practice, and their intention to leave direct patient care.

What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Behavior+10

+ Mental Disorders

+ Behavioral Symptoms

+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: August 2025
See protocol details

Summary

Principal SponsorUniversity of Fribourg
Study Contactmarco mancinetti, MDMore contacts
Last updated: July 16, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2025

Actual date on which the first participant was enrolled.

The COMET Study focuses on General Internal Medicine (GIM) residents in Switzerland. The study aims to understand the challenges faced by these young doctors, as fewer of them are choosing to stay in this specialty, despite an increasing need for GIM physicians due to an aging, multimorbid population. The study seeks to link the well-being, mental and physical health, and work-life balance of GIM residents to their actual career paths, as these factors are known to influence career decisions and patient care quality. This research is important as it can provide insights into how to improve the working conditions and well-being of GIM residents, potentially attracting more young doctors to the specialty and enhancing patient care. Participants in the COMET Study are GIM residents from three hospitals in Switzerland who provide direct patient care. They are asked to complete an annual online survey for at least four years, covering various aspects such as job characteristics, career intentions, well-being, mental health, and physical health. The study measures the changes in psychological distress, professional fulfillment, burnout, and depressive symptoms among the participants. It also tracks the percentage of participants who continue their training or practice in GIM versus those who switch to another specialty or leave clinical medicine. The study uses established scales like the Physician Well-Being Index, Professional Fulfillment Index, and Center for Epidemiologic Studies-Depression scale to assess these factors.

Principal SponsorUniversity of Fribourg
Study Contactmarco mancinetti, MDMore contacts
Last updated: July 16, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

800 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorMental DisordersBehavioral SymptomsNervous System DiseasesSigns and SymptomsSleep Wake DisordersStress, PsychologicalPathological Conditions, Signs and SymptomsSleep Disorders, IntrinsicDyssomniasBurnout, PsychologicalFatigueSleep Initiation and Maintenance Disorders

Criteria

1 inclusion criteria required to participate
Resident physician in general internal medicine employed at a participating study site or annex centre during the recruitment period Written informed consent

1 exclusion criteria prevent from participating
Not providing direct patient care Severe mental or physical condition precluding informed consent or compliance with the protocol

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 3 locations

Recruiting

Inselspital - University Hospital

Bern, SwitzerlandOpen Inselspital - University Hospital in Google Maps
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HFR - Hôpital Cantonal

Fribourg, Switzerland
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CHUV - University Hospital

Lausanne, Switzerland
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3 Study Centers