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Skin Barrier Function Comparison in Women Using and Not Using UV Nail Lamps

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Study Aim

This observational study aims to compare the skin barrier function in women who use UV nail lamps and those who do not, by measuring changes in transepidermal water loss, skin hydration, and skin erythema.

What is being collected

Data Collection

Collected at a single point in time - Cross-sectional
Who is being recruted

Signs and Symptoms+3

+ Skin Diseases

+ Skin Manifestations

From 18 to 50 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
Study Start: July 2026
See protocol details

Summary

Principal SponsorUniversity of Split, School of Medicine
Study ContactJosipa BukićMore contacts
Last updated: July 13, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: July 1, 2026

Actual date on which the first participant was enrolled.

This study focuses on comparing the skin's protective barrier in healthy adult women who regularly use UV lamps for nail treatments and those who do not. The main aim is to understand if regular use of UV lamps impacts the skin's barrier function. The study also explores if the duration of UV lamp use influences the skin's protective abilities. This research holds significance as it can provide insights into the potential effects of UV lamps on skin health, addressing a common yet often overlooked aspect of beauty routines. Participants in this study will attend a single visit where they will complete a brief questionnaire about their nail care habits and the duration of UV lamp use. They will then undergo non-invasive tests to measure the skin's barrier function on their hands. These tests include assessing transepidermal water loss, which indicates how well the skin retains moisture, skin hydration levels, and skin redness or erythema. These measurements will help researchers understand the potential impact of UV lamps on various aspects of skin health.

Principal SponsorUniversity of Split, School of Medicine
Study ContactJosipa BukićMore contacts
Last updated: July 13, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

30 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 18 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Signs and SymptomsSkin DiseasesSkin ManifestationsPathological Conditions, Signs and SymptomsSkin and Connective Tissue DiseasesErythema

Criteria

3 inclusion criteria required to participate
Healthy adult women ( >= 18 years of age)

Willing and able to provide written informed consent

Willing to complete the study questionnaire

4 exclusion criteria prevent from participating
Pregnancy or breastfeeding

Active skin diseases (e.g., psoriasis, vitiligo, or other dermatological conditions)

Use of topical or systemic corticosteroids, immunosuppressive drugs, or antihistamines

Allergic contact dermatitis

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

University of Split School of Medicine

Split, CroatiaOpen University of Split School of Medicine in Google Maps
Recruiting
One Study Center