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Prenatal Music Exposure to Enhance Postnatal Language Development

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What is being tested

High dose music Exposure

+ Low dose music exposure

+ Education

Other
Who is being recruted

Behavior

+ Communication

+ Language

Over 18 Years
+4 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Placebo-Controlled
Interventional
Study Start: September 2025
See protocol details

Summary

Principal SponsorChinese University of Hong Kong
Study ContactPeggy Chan, PhDMore contacts
Last updated: July 13, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: September 15, 2025

Actual date on which the first participant was enrolled.

\[BACKGROUND\] Fetuses can hear in the womb from as early as 20 weeks of gestation. Research has shown that prenatal music and spoken language experiences are related to better neural and behavioral outcomes at birth. These findings, though focused on outcomes shortly after birth, are consistent with a larger body of research showing positive effects of postnatal music training on children's language and cognitive outcomes. \[AIM OF STUDY\] Objective 1: To examine whether prenatal music exposure leads to better neural encoding of speech and better language and cognitive developmental outcomes up to two years of life. Objective 2: To construct predictive models using fetal data (e.g., fetal brain MRI and ultrasound data, if available) to forecast individual differences in developmental outcomes among fetuses exposed to prenatal music. \[HYPOTHESIS\] The investigators hypothesize that prenatal music exposure can strengthen a fetus's neural encoding of speech from birth, leading to better language and cognitive development in early childhood. The investigators further hypothesize that, despite the expected heterogeneity in intervention effects, fetal features can predict how much a fetus would benefit from prenatal music exposure.

NCT07699536
Principal SponsorChinese University of Hong Kong
Study ContactPeggy Chan, PhDMore contacts
Last updated: July 13, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

480 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorCommunicationLanguage

Criteria

4 inclusion criteria required to participate
single fetus pregnancy

Less than 32 weeks of gestation

aged 18 years or above

residents of the Greater Bay Area (GBA) with Cantonese and/or Putonghua being the primary home language(s)

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

3 intervention groups are designated in this study

33.333% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
Participants will be exposed to a higher dose of music

Group II

Active Comparator
Participants will be exposed to a lower dose of music

Group III

Placebo
Participants will learn independently from educational materials

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 2 locations

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BaoAn Hospital

Shenzhen, ChinaOpen BaoAn Hospital in Google Maps
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The Prince of Wales Hospital

Hong Kong, Hong Kong
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2 Study Centers