Recruiting
Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients
What is being tested
Probiotic (L. brevis CD2 lozenges)
+ Zinc chlorhexidine mouth wash
+ Probiotic (L. brevis CD2 lozenges)
OtherBehavioral
Who is being recruted
Signs and Symptoms+1
+ Signs and Symptoms, Digestive
+ Pathological Conditions, Signs and Symptoms
From 18 to 30 Years
+6 Eligibility Criteria
How is the trial designed
Supportive Care Study
Interventional
Study Start: December 2025
Summary
Principal SponsorSara M Almshhadany
Study ContactSara M Almshhadany, assistant professorMore contacts
Last updated: July 9, 2026Sourced from a government-validated database.Claim as a partner
Study start date: December 31, 2025
Actual date on which the first participant was enrolled.Do probiotics and Zn/CHx mouthwashes have an effect on plaque accumulation and halitosis in fixed orthodontic patients?
Principal SponsorSara M Almshhadany
Study ContactSara M Almshhadany, assistant professorMore contacts
Last updated: July 9, 2026Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
60 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Supportive Care Study
These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.From 18 to 30 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Signs and SymptomsSigns and Symptoms, DigestivePathological Conditions, Signs and SymptomsHalitosis
Criteria
3 inclusion criteria required to participate
good medical health
no systematic disease
non consuming drugs known to influence salivary flow, halitosis, or oral microbiota
3 exclusion criteria prevent from participating
smokers, pregnant and lactating womens
alcohol drinking
allergy or intolerance to corticosteroid treatment, antibiotic, antimicrobial mouth rinses, oral spray or tongue scraper, anti-inflammatory drugs or probiotics
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
halitosis
Group II
1\. Plaque accumulation
Study Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Recruiting
Recruiting
One Study Center