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Comparison of Intracuticular Suture Alone and With Skin Adhesive for Cesarean Delivery Scar Healing

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Study Aim

This study compares the healing of cesarean delivery scars when using intracuticular sutures alone versus combining them with skin adhesive, focusing on potential skin complications such as infections, seroma, skin opening, and other skin-related issues.

What is being tested

Dermabond

Other
Who is being recruted

Infections+3

+ Pathologic Processes

+ Postoperative Complications

Over 18 Years
+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: January 2025
See protocol details

Summary

Principal SponsorDoron Kabiri
Study ContactEfrat Shekel, MDMore contacts
Last updated: March 20, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 27, 2025

Actual date on which the first participant was enrolled.

This study looks at two different methods of closing the skin after a cesarean delivery: using only intracuticular sutures (stitches that are hidden under the skin) with a single thread, and using intracuticular sutures along with a biological adhesive material. The aim is to understand if one method leads to fewer skin scar complications than the other. The study also wants to find out which method results in better patient satisfaction, convenience, and scar healing and appearance. The study is important because both methods are commonly used, but there hasn't been a comparison between them yet. Women aged 18 and above who are having a planned cesarean delivery at the Hadassa medical center are eligible to participate. Participants will be randomly assigned to one of the two methods of skin closure. They will be asked to complete a questionnaire two days after the surgery. Six to eight weeks after the surgery, they will have an in-person check-up with their surgeon. At this check-up, they will fill out another questionnaire and have their scar appearance evaluated by the surgeon. The study will look at any skin complications, including superficial or deep infections, seroma (fluid build-up), skin opening, the need for antibiotics, and skin-related issues like rash, itching, and discharge.

Official TitleIntracuticular Suture Alone Compared to Intracuticular Suture and Skin Adhesive Material for Skin Closure After Cesarean Delivery : a Prospective Randomized Control Study
Principal SponsorDoron Kabiri
Study ContactEfrat Shekel, MDMore contacts
Last updated: March 20, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

240 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

InfectionsPathologic ProcessesPostoperative ComplicationsSurgical Wound InfectionPathological Conditions, Signs and SymptomsWound Infection

Criteria

1 inclusion criteria required to participate
Patients undergoing elective cesarean section at Hadassa medical center

1 exclusion criteria prevent from participating
Patients undergoing emergency cesarean section, patients undergoing cesarean section before 37+0/7 weeks of gestation, patients with a history of previous wound complications after previous Caesarean section

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
This group will have their skin closed after a cesarean section using a special stitch and a biological glue. The stitch is called an intracuticular suture and the glue is a skin adhesive.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Hadassah University Medical Center, Ein Karem Campus

Jerusalem, IsraelOpen Hadassah University Medical Center, Ein Karem Campus in Google Maps
Recruiting
One Study Center