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Comparative Study on Non-Operative Treatment Strategies for Chopart Fractures

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Study Aim

This study aims to compare the effectiveness of different non-operative treatment strategies for Chopart fractures, with the primary focus on patient-reported outcomes measured using the European foot and ankle society score.

What is being tested

6 weeks cast immobilization

+ Rigide sole

Other
Who is being recruted

Over 18 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: October 2026
See protocol details

Summary

Principal SponsorHôpital Fribourgeois
Last updated: March 18, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 1, 2026

Actual date on which the first participant was enrolled.

This research study is about finding the best non-surgical treatment for Chopart fractures, a type of ankle injury. These fractures are becoming more common due to better detection methods. Currently, treatment options range from immobilizing the ankle for 6-8 weeks to more active rehabilitation. However, it's unclear which approach works best. The study is conducted at Hospital Cantonal Fribourg (HFR), where about 50 Chopart injuries are treated yearly. The hospital typically immobilizes the ankle for healing, but this can cause muscle weakness and stiffness. Newer research suggests that a more active treatment might yield better results, but it's uncertain if this leads to quicker recovery or increased pain and complications. The study's main goal is to compare these treatment strategies using patient feedback and objective gait analysis. Participants in this study will be randomly assigned to one of two treatment groups. The first group will have their ankle immobilized using a cast or a special boot for six weeks. This provides stable conditions for healing but may cause muscle weakness and stiffness. The second group will wear a rigid-sole shoe and bear weight as tolerated. This approach allows early movement, reducing muscle weakness and maintaining ankle mobility, but there may be concerns about pain and insufficient fracture stabilization. The study will measure patient-reported outcomes using a questionnaire that combines the European Foot and Ankle Society (EFAS) Score and the Short Form-12 health survey. It will also use objective gait analysis to assess recovery progress.

Official TitleChopart Injury, Randomized Trial
Principal SponsorHôpital Fribourgeois
Last updated: March 18, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

70 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

3 inclusion criteria required to participate
Patients aged above 18 years

Patient with a pure ligament Chopart injury or bony avulsion of the ligaments of the Chopart joint line

Patient expected to complete length of study

4 exclusion criteria prevent from participating
Patient which does not understand the informed consent (due to language capacity or mental capacity)

Patient non ambulating before time of injury

Patient treated for the fracture outside of Hopital Cantonal Fribourg (the study side)

Patient treated for a fracture at the same foot/ ankle before

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Active Comparator
Immobilization in a cast or VACOped boot for 6 weeks

Group II

Weightbearing as tolerated using a rigid-sole shoe.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
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