Lidocaine IV Infusion in Two Doses for Neuropathic Pain Post-Mastectomy
This study aims to prevent neuropathic pain post-mastectomy by administering Lidocaine IV in two doses, with the primary outcome being the assessment of your pain using a 10-item neuropathic pain scale.
Lidocaine 2%
+ Lidocaine
Nervous System Diseases+5
+ Neuralgia
+ Neurologic Manifestations
Prevention Study
Summary
Study start date: July 25, 2022
Actual date on which the first participant was enrolled.This study focuses on managing neuropathic pain, a type of pain often experienced by patients who have undergone mastectomy for breast cancer. The pain can be challenging to manage, with various drugs like opioids and antidepressants used, but these come with side effects. The study aims to find a safer and more effective solution by comparing two different doses of Lidocaine, an amide local anesthetic. Lidocaine has been found to provide pain relief in several chronic neuropathic conditions with fewer side effects. It's also known to have an opioid-sparing effect, meaning it can reduce the need for opioids. The study hopes to improve care for patients experiencing neuropathic pain after mastectomy. During the study, participants will receive Lidocaine through an IV injection. The study's primary goal is to assess the neuropathic pain scale, a tool designed to measure the distinct qualities and intensity of nerve-related pain. This scale helps distinguish neuropathic pain from other types of pain. It evaluates 10 specific qualities associated with neuropathic pain, such as burning, freezing, and stinging, using a 0-10 numerical rating for each. The study aims to understand how effectively Lidocaine manages these symptoms and improves the overall quality of life for patients.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.30 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Prevention Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Active ComparatorGroup II
Active ComparatorStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
National Cancer Institute, Cairo University
Cairo, EgyptOpen National Cancer Institute, Cairo University in Google Maps