Bonafide-HF3.0 Dietary Supplement for Vasomotor Symptoms in Women

This study focuses on the dietary supplement Bonafide-HF3.0 and its effect on women experiencing vasomotor symptoms, such as hot flashes and night sweats. The trial aims to enroll around 200 women across the U.S. who will take two tablets of the supplement every morning for four weeks. An optional eight-week extension is available for participants to continue taking the supplement at the same dose. This study is important as it aims to improve the quality of life for women experiencing menopausal symptoms by reducing the severity and frequency of hot flashes and night sweats. During the study, participants will have virtual check-ins, including a pre-screening visit, a screening visit, a baseline visit, and an initial end-of-study visit. If a participant chooses to join the eight-week extension, two additional virtual visits will be scheduled. Throughout the study, participants will complete daily diaries and weekly and monthly questionnaires to report on their symptoms and well-being. The primary outcomes measured include changes in hot flash symptoms, menopausal symptoms, and overall quality of life, using various scales such as the Hot Flash Related Daily Interference Scale (HFRDIS), the Visual Analog Scale Vasomotor Symptoms Questionnaire (VAS), the Greene Climacteric Scale (CGS), and the Menopause Rating Scale (MRS).