Prophylactic ciNPWT for High-risk Diabetic Patients in Acute Laparotomy Wounds

This clinical trial aims to investigate the effectiveness of a treatment called Prophylactic Negative Pressure Wound Therapy (ciNPWT) in high-risk diabetic patients who have undergone acute laparotomy, a type of abdominal surgery. Surgical site infections (SSIs) are a significant challenge in many surgical disciplines, despite preventive measures. Abdominal surgeries, especially those involving bowel resections, carry a higher risk of wound infections. For diabetic patients, uncontrolled diabetes can lead to complications, including wound infections, due to factors like tissue hypoxia and cellular dysfunction. This study is important as it could help improve care for diabetic patients undergoing abdominal surgeries by reducing the risk of SSIs. During the study, participants will receive ciNPWT treatment, which involves applying continuous or intermittent negative pressure to the surgical incision. This therapy increases tissue vascularization, reduces edema, and promotes wound healing by removing necrotic tissue debris and stimulating granulation tissue formation. The primary outcome measured in this study is the incidence of SSI, evaluated through clinical assessment and medical records. The study aims to determine if ciNPWT can reduce the number of patients developing surgical site infections after emergency laparotomy.