Completed

Personalized Music Impact on Dreaming During Propofol Sedation

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Study Aim

This study aims to investigate how personalized music during propofol sedation affects your dreaming experience, focusing on whether you dream and how pleasant those dreams are.

What is being tested

Preferred Music

+ Matched Non-Preferred Music

+ Silence (Headphones Only)

Behavioral
Who is being recruted

From 19 to 70 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Supportive Care Study

Placebo-Controlled
Interventional
Study Start: December 2025
See protocol details

Summary

Principal SponsorWonkwang University Hospital
Last updated: February 6, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 19, 2025

Actual date on which the first participant was enrolled.

This study is about understanding how personalized music and auditory stimulation can impact dreaming during sedation using Propofol, a common sedative. The study focuses on adults who are undergoing elective procedures under spinal anesthesia or peripheral nerve block with propofol sedation. The goal is to see if preferred music can increase dreaming and make it more pleasant, which could potentially improve the overall experience of sedation. This research is important as it could lead to better ways of managing patient comfort during medical procedures. Participants in this study are randomly assigned to one of three groups: Preferred Music, Matched Non-preferred Music, or Silence. Those in the Preferred Music group select a personally meaningful track that is played on loop through headphones during sedation. The Matched Non-preferred Music group listens to a pleasant non-selected track that is similar to the preferred selection in terms of tempo, genre, and loudness. The Silence group wears headphones but does not hear any music. The effects of the music are then measured by assessing dream incidence and dream pleasantness. Dream incidence is determined by asking participants if they had a dream, while dream pleasantness is rated on a scale from 0 to 10. The study also looks at other factors like patient satisfaction, sedative dose, and recovery endpoints.

Official TitlePersonalized Music Increases Dreaming During Propofol Sedation: A Randomized Trial Comparing Preferred Music, Matched Non-Preferred Music, and Silence
Principal SponsorWonkwang University Hospital
Last updated: February 6, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

300 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 19 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

4 inclusion criteria required to participate
Able to understand the study procedures and provide written informed consent.

Scheduled for an elective procedure under intravenous propofol sedation at Wonkwang University Hospital.

American Society of Anesthesiologists (ASA) physical status I-III.

Adults aged ≥ [19] years and ≤ [70] years.

6 exclusion criteria prevent from participating
Known hearing impairment that would interfere with headphone-based auditory intervention.

Use of sedatives, hypnotics, or psychoactive medications that could confound dreaming assessment, per protocol.

Pre-existing cognitive impairment or delirium at baseline (e.g., diagnosed dementia or active delirium).

Significant neurologic or psychiatric disorder that may affect dream recall/reporting.

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

3 intervention groups are designated in this study

33.333% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
Participants listen to their self-selected preferred music through standardized closed-back headphones during intravenous propofol sedation. Music starts at the beginning of sedation and continues until the end of the procedure/recovery period per protocol.

Group II

Experimental
Participants listen to non-preferred music matched to the preferred-music selection (e.g., comparable tempo/energy/genre characteristics) through standardized closed-back headphones during intravenous propofol sedation. Playback timing and volume are standardized as in the preferred-music arm.

Group III

Placebo
Participants wear standardized closed-back headphones during intravenous propofol sedation, but no audio is played (silence condition). Procedures, timing, and staff interactions are otherwise identical to the music arms.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

IRB of Wonkwnag University Hospital

Iksan, South KoreaOpen IRB of Wonkwnag University Hospital in Google Maps
CompletedOne Study Center
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