Efficacy Evaluation of iRoot SP and nRoot SP in Chronic Apical Periodontitis

This clinical trial focuses on patients with chronic apical periodontitis, a condition that affects the tip of the tooth root and surrounding tissues. The study compares the effectiveness of two domestically produced sealer pastes, iRoot SP and nRoot SP, used in root canal treatments. The main goal is to evaluate how well these materials work over a period of 3 to 24 months, looking at factors like reduction in swelling and pain, and improvement in chewing function. This study is important as it aims to provide reliable evidence for the optimal use and selection of these materials in clinical practice, ultimately improving treatment outcomes for patients with chronic apical periodontitis. During the trial, participants receive a root canal treatment using either iRoot SP or nRoot SP sealer paste. The effectiveness of the treatment is measured through post-treatment X-ray examinations, which look for changes in the size of the affected area at the tooth root tip. Additionally, the study evaluates improvements in symptoms such as gingival swelling/pain, tooth discoloration, and occlusal discomfort, as well as restoration of chewing function. The potential benefits for participants include improved dental health and reduced symptoms, while the risks are those typically associated with root canal treatments.