Completed

CCLS-ICBComparative Study on Hemidiaphragmatic Function: Costoclavicular vs. Lateral Sagittal Infraclavicular Block

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Study Aim

This study compares the impact of two different block techniques, costoclavicular and lateral sagittal infraclavicular, on the movement of your diaphragm during normal and deep breathing, as measured by ultrasound.

What is being tested

Ultrasound-guided Infraclavicular block

Procedure
Who is being recruted

From 18 to 80 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: October 2022
See protocol details

Summary

Principal SponsorGazi University
Last updated: February 6, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 15, 2022

Actual date on which the first participant was enrolled.

This study focuses on comparing two different ultrasound-guided techniques for infraclavicular brachial plexus block, which are used to numb the arm for forearm, wrist, or hand surgery. The techniques are called costoclavicular and lateral sagittal approaches. The study is particularly interested in how these techniques affect the movement of half of the diaphragm, a muscle that helps us breathe. Adults scheduled for elective forearm or hand surgery are invited to participate in this study, which aims to improve the safety and effectiveness of regional anesthesia for upper extremity surgery. Participants in this study will receive either a costoclavicular or a lateral sagittal infraclavicular nerve block using a medication called bupivacaine, under ultrasound guidance. The study measures the movement of the diaphragm during normal and deep breathing using ultrasound to assess the effect of these block techniques. Other aspects evaluated include sensory and motor block characteristics, pain scores after surgery, pain medication requirements, and potential complications related to the block. The results of this study will help guide anesthesiologists in choosing the most appropriate technique for upper extremity surgery.

Official TitleEffect of Costoclavicular Versus Lateral Sagittal Infraclavicular Block on Hemidiaphragmatic Function: A Randomized Clinical Study
Principal SponsorGazi University
Last updated: February 6, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

91 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Inclusion Criteria: * Adults aged 18-80 years * ASA physical status I-III * Scheduled for forearm, wrist, or hand surgery * Planned infraclavicular brachial plexus block Exclusion Criteria: * Refusal of regional anesthesia * Known allergy to local anesthetics * Infection at the block site * Pre-existing neurological deficit in the operative limb * Severe pulmonary disease * Coagulopathy or sepsis * BMI \> 40 kg/m² * Psychiatric disorders

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Ultrasound-guided costoclavicular infraclavicular brachial plexus block

Group II

Active Comparator
Ultrasound-guided lateral sagittal infraclavicular brachial plexus block

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Gazi University Faculty of Medicine, Department of Anesthesiology and Reanimation

Ankara, Turkey (Türkiye)Open Gazi University Faculty of Medicine, Department of Anesthesiology and Reanimation in Google Maps
CompletedOne Study Center