Botulinum Toxin vs Platelet Rich Fibrin Injection for Temporomandibular Joint Internal Derangement Treatment

This study focuses on a common condition called Temporomandibular Joint (TMJ) internal derangement, which often causes pain and difficulty in moving the jaw. People with this condition may experience pain while chewing, struggle with opening their mouth, hear clicking or crackling sounds in their jaw, and feel pain around their ear. The study aims to compare two different treatments: Botulinum Toxin Type A (BOTOX) and injectable platelet-rich fibrin (I-PRF). The goal is to see which treatment works better in reducing symptoms and improving jaw function for those with TMJ internal derangement. In this study, 20 patients with TMJ internal derangement are randomly divided into two groups. One group receives I-PRF injections directly into the affected jaw joint, while the other group gets BOTOX injections into a specific jaw muscle. Over a period of six months, patients are evaluated at different intervals. Check-ups include assessing pain levels, measuring how wide the mouth can open, examining jaw movements, and checking for tenderness in the jaw muscles and joint. Magnetic Resonance Imaging (MRI) is also used to observe changes in the joint structure and disc position after treatment. The study's results will help determine which treatment, I-PRF or BOTOX, provides better improvement in symptoms and joint condition.