Assessment of Conjunctival Inflammation in Soft Contact Lens Wearers Using Image J Analysis and Efron Degree System
This study aims to assess the level of conjunctival inflammation in soft contact lens wearers using Image J Analysis and Efron Degree System.
hydrogel soft contact lens
Other Study
Summary
Study start date: March 28, 2019
Actual date on which the first participant was enrolled.This study focuses on individuals with myopia, or nearsightedness, who are new to soft contact lenses (SCL). The main goal is to understand how soft contact lenses might affect the eye, specifically looking at conjunctival inflammation, which is redness or swelling of the thin tissue lining the white part of the eye. Participants are asked to wear soft contact lenses for 14 days, a period during which the study aims to gather valuable insights into how soft contact lenses might impact eye health in new users. During the study, participants undergo slit lamp examinations, a common eye test that allows a detailed look at the eye. These examinations are conducted before they start wearing soft contact lenses, and then again on the 7th and 14th day of wearing them. The results of these examinations are analyzed using two methods: the Efron Degree System (EDS) and ImageJ, a software tool for image analysis. By comparing these two methods, the study aims to evaluate how effectively they can assess any changes in conjunctival inflammation over the course of soft contact lens use.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.52 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Other Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 45 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Inclusion Criteria: * subject with mild to moderate myopia (-0.50 to -6.00 D) * age between 18-45 years old * subject who refuse refractive correction with glasses or surgery * patient with astigmatism refractive error no more than -1 Diopter Exclusion Criteria: * subject with previous intraocular surgery * subject who is wearing SCL continuously * subject with history of dry eyes, uveitis, glaucoma, or corneal and conjunctival disorders * subject with history of allergic reaction to contact lens material or lens wetting solution used in this study * subject with ongoing eye drop treatment * female subject with ongoing pregnancy or on breastfeeding * subject with too improper lens fitting * subject who work around exposure of chemical substance, smoke, hazardous gas, or fire sparks
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalStudy Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Department of Ophthalmology, Faculty of Medicine Universitas Indonesia Cipto Mangunkusumo Hospital, Indonesia
Jakarta, IndonesiaOpen Department of Ophthalmology, Faculty of Medicine Universitas Indonesia Cipto Mangunkusumo Hospital, Indonesia in Google Maps