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Pain Neuroscience Education and Sensory Training for Chronic Low Back Pain

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Study Aim

This study aims to see if pain neuroscience education and sensory training can help reduce negative thoughts about pain in people with chronic low back pain.

What is being tested

Pain Neuroscience Education with Sensory Discrimination Training and Core Stability Exercises

+ Pain Neuroscience Education and Core stability Exercises

Other
Who is being recruted

Kinesiophobia+7

+ Anxiety Disorders

+ Back Pain

From 19 to 44 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: December 2025
See protocol details

Summary

Principal SponsorLahore University of Biological and Applied Sciences
Study ContactMUHAMMAD SAAD JANJUAMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 1, 2025

Actual date on which the first participant was enrolled.

This study is focused on helping people who suffer from long-term low back pain, which is affected by various physical and psychological factors. The research explores whether combining two treatment methods, Pain Neuroscience Education and Sensory Discrimination Training, along with core stability exercises, can be more effective than just using Pain Neuroscience Education and exercises alone. Pain Neuroscience Education helps change the way people think about pain, while Sensory Discrimination Training works on improving sensory processing in the brain. This combination is being studied to see if it can reduce negative thinking about pain, decrease fear of movement, and improve physical function for individuals with chronic low back pain. Participants in this study are randomly assigned to two groups. One group receives Pain Neuroscience Education, Sensory Discrimination Training, and core stability exercises, while the other group receives just the education and exercises without the sensory training. These sessions happen twice a week for eight weeks and last 45 minutes each. Researchers measure changes in how participants think about pain, their fear of movement, and their physical abilities over time, specifically at the start, after four weeks, and at the end of the eight weeks. This study is conducted in Lahore to ensure consistent treatment and aims to see if adding Sensory Discrimination Training can lead to better outcomes for those with chronic low back pain.

Official TitleEffects of Pain Neuroscience Education With Sensory Discrimination Training on Pain Catastrophizing, Kinesiophobia and Functional Movements Among Patients With Chronic Low Back Pain: A Randomized Controlled Trial
Principal SponsorLahore University of Biological and Applied Sciences
Study ContactMUHAMMAD SAAD JANJUAMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

80 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 19 to 44 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

KinesiophobiaAnxiety DisordersBack PainMental DisordersNeurologic ManifestationsPainPhobic DisordersSigns and SymptomsPathological Conditions, Signs and SymptomsLow Back Pain

Criteria

Inclusion Criteria: * Age: 19 to 44 Both Genders Mechanical low back pain (duration more than 6 months and less than 2 years) \>4/10 Numerical Pain Rating Scale (NPRS) Exclusion Criteria: * Pregnancy or post-partum Trauma Psychological Pain Radicular Pain Cancer, tumor, malignancy Neurological Deficit Recent Surgery \<1year

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Participants in the experimental group will receive a 45-minute intervention session consisting of three integrated components (Pain Neuroscience Education, Core Stability Exercises and Graded Sensory Discrimination Training )

Group II

Active Comparator
Participants in the control group will receive the same 45-minute sessions consisting of two components (Pain Neuroscience Education and Core Stability Exercises).

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
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