Tirzepatide for Obesity in Adults Without Diabetes
This study evaluates the effectiveness of Tirzepatide in reducing body weight in adults with obesity who do not have diabetes.
Tirzepatide
+ Standard of Care
Body Weight+5
+ Nutrition Disorders
+ Nutritional and Metabolic Diseases
Treatment Study
Summary
Study start date: November 24, 2025
Actual date on which the first participant was enrolled.The study is designed to evaluate the effectiveness of a medication called tirzepatide in helping people with obesity lose weight and prevent the onset of type 2 diabetes. This study specifically focuses on adults who are obese and have at least one other health condition related to their weight, but who do not currently have diabetes. By testing tirzepatide in a real-world setting, the study aims to see if this treatment can offer a new, effective option for weight management and diabetes prevention in this population. Participants in this study will take tirzepatide once a week. The study will compare the results of those taking tirzepatide with those receiving standard care for obesity. Researchers will primarily look at changes in body weight from the start of the study to see how effective the treatment is. The study will last about 260 weeks, allowing enough time to observe long-term effects and any potential benefits of this treatment approach.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.3000 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
Active ComparatorStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 25 locations
P89008 Ashton Medical Group
Ashton-under-Lyne, United KingdomOpen P89008 Ashton Medical Group in Google MapsP89002 The Brooke Surgery
Hyde SK14, United KingdomP86004 Peterloo Medical Centre
Manchester, United KingdomP87019 Silverdale Medical Practice
Manchester, United Kingdom