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Digital Mental Health Intervention for Adolescents with Nonsuicidal Self-injury

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Study Aim

This study aims to evaluate the acceptability and appropriateness of a digital mental health intervention for adolescents who engage in nonsuicidal self-injury.

What is being tested

App-based digital mental health intervention for adolescent NSSI

+ App-based delivery of healthy living psychoeducational materials

Device
Who is being recruted

Anxiety Disorders+3

+ Behavior

+ Mental Disorders

From 14 to 18 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: January 2026
See protocol details

Summary

Principal SponsorNorthwestern University
Study ContactKaylee Kruzan, PhD, LCSW
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2026

Actual date on which the first participant was enrolled.

This study focuses on creating and testing a new digital mental health tool for teenagers aged 14 to 18 who engage in nonsuicidal self-injury (NSSI). It targets adolescents not currently in treatment and aims to provide them with psychoeducation and skills through an interactive digital platform. This tool is important because it could offer a new way to support young people struggling with self-injury, helping them learn new skills and potentially reducing the frequency and severity of their self-injury behaviors. The study addresses a significant need for accessible mental health resources for adolescents who might not seek traditional forms of treatment. Participants in the study are randomly assigned to one of two groups: one group receives the digital mental health intervention, while the other receives a psychoeducational control over eight weeks. The digital intervention includes engaging activities and interactive conversations aimed at teaching coping skills. Researchers will measure the success of this study by looking at how often and how severely participants engage in self-injury, as well as their willingness to seek help. The study also evaluates how acceptable and appropriate participants find the intervention. Participants must have access to a smartphone, be proficient in English, and cannot have severe mental health conditions or be at high risk of suicide. They are allowed to seek other treatments once they join the study.

Official TitleDeveloping a Digital Intervention for Adolescent Nonsuicidal Self-injury
NCT07224165
Principal SponsorNorthwestern University
Study ContactKaylee Kruzan, PhD, LCSW
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

80 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 14 to 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Anxiety DisordersBehaviorMental DisordersBehavioral SymptomsDepressionSelf-Injurious Behavior

Criteria

4 inclusion criteria required to participate
Current NSSI (NSSI on 2 or more days in the last month

English language skills sufficient to engage in the consent and intervention procedures

Age 14-18

Access to smartphone

3 exclusion criteria prevent from participating
Severe mental health diagnoses for which this intervention would be inappropriate (psychotic disorders, active manic episodes)

Severe suicide risk, including suicidal ideation with a plan and intent to act

Current engagement in psychotherapy

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
This is the experimental condition

Group II

Active Comparator
This is the comparison condition

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has no location dataSave this study to your profile to know when the location data is available.
Recruiting soonNo study centers