RENEW 2Cagrilintide for Weight Management in Overweight or Obesity with Type 2 Diabetes
This study aims to evaluate the effectiveness of Cagrilintide for weight management in individuals who are overweight or have obesity and are also living with type 2 diabetes.
Cagrilintide
+ Placebo (matched to Cagrilintide)
Body Weight+10
+ Diabetes Mellitus
+ Diabetes Mellitus, Type 2
Treatment Study
Summary
Study start date: November 5, 2025
Actual date on which the first participant was enrolled.This clinical trial investigates whether a new medicine called cagrilintide can help people who are overweight or have obesity, as well as type 2 diabetes, to lose weight. This study is important because managing weight is a crucial part of controlling type 2 diabetes, which can be challenging for many people. Cagrilintide is still under study and not yet available for doctors to prescribe. By exploring its effectiveness and safety, this research aims to contribute to potential new treatments that could support better health outcomes for those struggling with these conditions. In the study, participants will receive either cagrilintide or a placebo, which is a substance with no active medication. The assignment to either the medicine or placebo is random, but participants have a higher chance, specifically two times more likely, of receiving cagrilintide. The medication or placebo will be administered, and participants will be monitored for any changes in body weight and possible side effects. The entire duration of the study for each participant is approximately one year and six months, allowing researchers to gather comprehensive data on the long-term effects and safety of cagrilintide.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.330 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
50% chance of being blinded to the placebo group
Treatment Groups
Group I
ExperimentalGroup II
PlaceboStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 69 locations
Chambliss Clinical Trials, LLC
Montgomery, United StatesElite Clinical Network - Tucson
Tucson, United StatesScripps Whittier Diabetes Inst
La Jolla, United States