Recruiting soon

Microvascular Decompression for Trigeminal Neuralgia: Post-Operative Trigeminal Pain Study

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Study Aim

This study observes how pain control, measured by the Barrow Neurological Institute (BNI) Pain Scale, changes in Trigeminal Neuralgia patients after undergoing microvascular decompression surgery.

What is being collected

Data Collection

Collected from past medical records and data - Retrospective
Who is being recruted

Cranial Nerve Diseases+12

+ Facial Nerve Diseases

+ Facial Neuralgia

Over 18 Years
+3 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Other

Utilizing specific methods not covered by standard models in order to address unique research questions.
Observational
Study Start: December 2025
See protocol details

Summary

Principal SponsorRutgers, The State University of New Jersey
Study ContactSowmya Akkineni, BDSMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 12, 2025

Actual date on which the first participant was enrolled.

This study is designed to understand the long-term effects of a surgical procedure called microvascular decompression (MVD) in people who suffer from trigeminal neuralgia, a condition that causes severe facial pain. The main focus is to determine if certain activities, like undergoing dental treatment or experiencing other types of face-related procedures after the surgery, can lead to a return of the pain. This research is important because it seeks to find if these actions could potentially trigger pain again, which might help in improving the guidance given to patients after their surgery and lead to better management of their condition. Participants in this study are individuals who have already had the MVD surgery as part of their regular medical treatment. Instead of coming to a clinic, these participants will answer questions over the phone. The surveys will gather information about their experiences with pain after the surgery, including when it happens, if it is connected to anxiety, and if there have been any pain relapses. Additionally, the study will explore whether any dental or facial procedures they had after the surgery might relate to their pain experiences. This approach helps the researchers collect valuable data without requiring participants to travel, making the process more convenient.

Official TitlePost-Operative Trigeminal Pain After Microvascular Decompression for Trigeminal Neuralgia
NCT07216547
Principal SponsorRutgers, The State University of New Jersey
Study ContactSowmya Akkineni, BDSMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

100 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Other

Some studies use unique or mixed approaches that don't fit standard categories. These may include innovative observational methods or studies tailored to specific research questions.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Cranial Nerve DiseasesFacial Nerve DiseasesFacial NeuralgiaStomatognathic DiseasesMouth DiseasesNervous System DiseasesNeurologic ManifestationsPainPain, PostoperativePathologic ProcessesPostoperative ComplicationsSigns and SymptomsPathological Conditions, Signs and SymptomsTrigeminal NeuralgiaTrigeminal Nerve Diseases

Criteria

1 inclusion criteria required to participate
MVD post-operative patients with type I Trigeminal Neuralgia.

2 exclusion criteria prevent from participating
Atypical (Type II) Facial Pain at presentation, revision surgery.

Patients who are unable or unwilling to provide informed consent will be excluded from the study.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Rutgers School of Dental Medicine

Newark, United StatesOpen Rutgers School of Dental Medicine in Google Maps
Recruiting soonOne Study Center