Recruiting soon
PhP-VX

Parents Helping Parents Program for Youth Vaping Cessation

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Parents Helping Parents program

Behavioral
Who is being recruted

Implementation Science
+4

+ Engagement, Patient
+ E Cigarette Use
From 15 to 18 Years

See all eligibility criteria

How is the trial designed

Treatment Study

Interventional
Study Start: November 2025

See protocol details

Summary

Principal SponsorUniversity of Nebraska
Study ContactDaisy Dai, PhD
Last updated: October 6, 2025
Sourced from a government-validated database.Claim as a partner
Study start date: November 1, 2025Actual date on which the first participant was enrolled.

The study focuses on creating and testing a new program called Parents-helping-Parents for Youth Vaping Cessation (PhP-VX). This program is designed to help parents support their children in quitting vaping. The study aims to see if this program is feasible and effective. It involves 100 pairs of parents and adolescents, who are recruited through an electronic health record system. Half of these pairs will participate in the PhP-VX program, while the other half will not receive any specific treatment during the study period. This research is important as it explores a novel way to tackle the issue of youth vaping, which is a growing concern for families and society, potentially offering new strategies for cessation. Participants in the PhP-VX program will engage in online lessons and receive personalized coaching sessions. Parents will have six bi-weekly, 30-minute sessions with a coach over Zoom to learn skills like effective communication and decision-making, and to receive support. Both groups will be surveyed at the start and then at 1, 3, and 6 months to track their e-cigarette use and knowledge. Some adolescents will also have the option to provide saliva samples to measure nicotine-related substances, further validating the study's findings. After the study, the control group will receive access to the online training materials. This structured approach helps evaluate the potential benefits of the program in reducing vaping among adolescents.

Official TitleParents Helping Parents for Youth Vaping Cessation (PhP-VX) 
Principal SponsorUniversity of Nebraska
Study ContactDaisy Dai, PhD
Last updated: October 6, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details
200 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.
Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

How participants are assigned to different groups/arms
In this clinical study, participants are placed into groups randomly, like flipping a coin. This ensures that the study is fair and unbiased, making the results more reliable. By assigning participants by chance, researchers can better compare treatments without external influences.

Other Ways to Assign Participants
Non-randomized allocation: Participants are assigned based on specific factors, such as their medical condition or a doctor's decision.
None (Single-arm trial): If the study has only one group, all participants receive the same treatment, and no allocation is needed.

How treatments are given to participants
Participants are divided into different groups, each receiving a specific treatment at the same time. This helps researchers compare how well different treatments work against each other.

Other Ways to Assign Treatments
Single-group assignment: Everyone gets the same treatment.
Cross-over assignment: Participants switch between treatments during the study.
Factorial assignment: Participants receive different combinations of treatments.
Sequential assignment: Participants receive treatments one after another in a specific order, possibly based on individual responses.
Other assignment: Treatment assignment does not follow a standard or predefined design.

How the effectiveness of the treatment is controlled
In a non placebo-controlled study, no participants receive an inert substance (placebo) to compare outcomes. Instead, all participants receive either the experimental treatment or an alternative treatment (often the Standard of Care). This method allows researchers to compare the effects of the experimental treatment with those of a different active intervention, rather than a placebo.

Other Options
Placebo-Controlled: A placebo is used to compare the effects of the experimental treatment with those of an inert substance, isolating the true treatment effect.

How the interventions assigned to participants is kept confidential
Everyone involved in the study knows which treatment is being given. This is typically used when it's not possible or necessary to hide the treatment details from participants or researchers.

Other Ways to Mask Information
Single-blind: Participants do not know which treatment they are receiving, but researchers do.
Double-blind: Neither participants nor researchers know which treatment is given.
Triple-blind: Participants, researchers, and outcome assessors do not know which treatment is given.
Quadruple-blind: Participants, researchers, outcome assessors, and care providers all do not know which treatment is given.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria
Any sexBiological sex of participants that are eligible to enroll.
From 15 to 18 YearsRange of ages for which participants are eligible to join.
Healthy volunteers not allowedIf individuals who are healthy and do not have the condition being studied can participate.
Conditions
Pathology
Implementation Science
Engagement, Patient
E Cigarette Use
Peer Support
Vaping Teens
Vaping Cessation
Parent Support
Criteria

ADOLESCENT INCLUSION: * 15-18 * Report vaping in the previous 30 days * English literacy PARENT INCLUSION: * Biological, adoptive, stepparents, or adult guardian of adolescent participating * Have face-to-face contact with the adolescent at least one day per week during the study period * Access to a computer or mobile phone at home * Interested in helping adolescent quit e-cigarette/vape use

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives
2 intervention groups 

are designated in this study

This study does not include a placebo group 

Treatment Groups
Group I
No Intervention
Participants in this arm will not receive the PhP-VX treatment.
Group II
Experimental
Participants in this arm will receive the PhP-VX program.
Study Objectives
Primary Objectives

Secondary Objectives

Self-reported vaping intensity will be assessed with the questions "In the past 7 days, on the days you vaped, how many times did you usually pick up your device to vape? "and "In the past 7 days, each time you pick up your vape, how many puffs do you usually take before putting it away?".

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has 1 location
Suspended
University of Nebraska Medical CenterOmaha, United StatesSee the location
Recruiting soonOne Study Center