Recruiting
Brief Relief

Mindfulness Intervention for Chronic Musculoskeletal Pain Relief

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Brief Mindfulness Oriented Recovery Enhancement

+ Empowered Relief
+ Mindfulness Oriented Recovery Enhancement
Behavioral
Who is being recruted

Chronic Musculoskeletal Pain

Over 18 Years
+2 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Treatment Study

Interventional
Study Start: August 2025

See protocol details

Summary

Principal SponsorFlorida State University
Study ContactAdam Hanley, PhD
Last updated: September 25, 2025
Sourced from a government-validated database.Claim as a partner
Study start date: August 14, 2025Actual date on which the first participant was enrolled.

The study conducted by researchers at Florida State University focuses on finding the optimal treatment duration for people suffering from chronic musculoskeletal pain. This condition includes long-term pain affecting muscles, bones, and joints. The study aims to determine how different lengths of pain management training can help reduce pain effectively. By comparing two brief training sessions against a standard-length training session, the researchers hope to identify the best approach that provides significant pain relief while being time-efficient for patients. This research is important as it could lead to more effective and accessible pain management strategies for those dealing with chronic pain. Participants in this study will be randomly assigned to one of three groups. Two groups will participate in a brief, single 2-hour online session, while the third group will attend eight weekly 2-hour online sessions. In all sessions, a trained facilitator will teach pain management techniques that have been proven to be effective through research. Participants will also complete short surveys at various stages: before starting the treatment, right after the session, and over several weeks afterward, to track their pain levels and the effectiveness of the training. This design helps researchers understand not only how well the techniques work immediately but also their lasting impact over time.

Official TitleBrief MORE: A Mindfulness Intervention For Chronic Musculoskeletal Pain 
Principal SponsorFlorida State University
Study ContactAdam Hanley, PhD
Last updated: September 25, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details
39 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.
Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

How participants are assigned to different groups/arms
In this clinical study, participants are placed into groups randomly, like flipping a coin. This ensures that the study is fair and unbiased, making the results more reliable. By assigning participants by chance, researchers can better compare treatments without external influences.

Other Ways to Assign Participants
Non-randomized allocation: Participants are assigned based on specific factors, such as their medical condition or a doctor's decision.
None (Single-arm trial): If the study has only one group, all participants receive the same treatment, and no allocation is needed.

How treatments are given to participants
Participants are divided into different groups, each receiving a specific treatment at the same time. This helps researchers compare how well different treatments work against each other.

Other Ways to Assign Treatments
Single-group assignment: Everyone gets the same treatment.
Cross-over assignment: Participants switch between treatments during the study.
Factorial assignment: Participants receive different combinations of treatments.
Sequential assignment: Participants receive treatments one after another in a specific order, possibly based on individual responses.
Other assignment: Treatment assignment does not follow a standard or predefined design.

How the effectiveness of the treatment is controlled
In a non placebo-controlled study, no participants receive an inert substance (placebo) to compare outcomes. Instead, all participants receive either the experimental treatment or an alternative treatment (often the Standard of Care). This method allows researchers to compare the effects of the experimental treatment with those of a different active intervention, rather than a placebo.

Other Options
Placebo-Controlled: A placebo is used to compare the effects of the experimental treatment with those of an inert substance, isolating the true treatment effect.

How the interventions assigned to participants is kept confidential
Participants do not know which treatment they are receiving, but researchers do. This helps prevent bias from participants' expectations while still allowing researchers to monitor the study closely.

Other Ways to Mask Information
Open-label: Everyone knows which treatment is being given.
Double-blind: Neither participants nor researchers know which treatment is given.
Triple-blind: Participants, researchers, and outcome assessors do not know which treatment is given.
Quadruple-blind: Participants, researchers, outcome assessors, and care providers all do not know which treatment is given.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria
Any sexBiological sex of participants that are eligible to enroll.
Over 18 YearsRange of ages for which participants are eligible to join.
Healthy volunteers not allowedIf individuals who are healthy and do not have the condition being studied can participate.
Conditions
Pathology
Chronic Musculoskeletal Pain
Criteria
1 inclusion criteria required to participate
(1) having a chronic musculoskeletal pain condition, (2) average pain of ≥ 3 in the previous week, (3) willingness to engage with study assessments and interventions, (4) understanding English instructions fluently, and (5) being 18 and above
1 exclusion criteria prevent from participating
(1) unable to consent because of physical or mental incapacity, (2) have previous, formal mindfulness training (e.g., MBSR) or previously receiving Empowered Relief, (3) have pain from a current cancer diagnosis or cancer-related treatment, (4) unstable illness that may interfere with treatment, (5) had surgery within the previous three months, and (6) had pain relieving injections, such as cortisone or hyaluronate, within the previous three months

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives
3 intervention groups 

are designated in this study

This study does not include a placebo group 

Treatment Groups
Group I
Experimental
B-MORE is a 2-hour, single session adaptation of the traditional MORE program.
Group II
Experimental
ER is an evidence-based 2-hour single session intervention for chronic pain
Group III
Experimental
MORE is an 8-week evidence-based treatment for chronic pain.
Study Objectives
Primary Objectives

Recruitment feasibility will be assessed via total enrollment and randomization numbers within the first 6 months of the study. Study team projects that it will be feasible to recruit and randomize 30 adults with CMP within 6 months.

Adherence (percentage of total treatment time attended) will be better for the single-session interventions, but all three conditions will be rated as highly acceptable (as measured by the Theoretical Framework of Acceptability; TFA).
Secondary Objectives

A 3-item questionnaire using a 5-point Likert-like scale (1- had no pain to 5- very severe). Questions include "In the past 7 days, How intense was your pain at its worst?"

An 8-item questionnaire using a 5-point Likert-like scale (1- not at all to 5- very much). Questions include "In the past 7 days, how much did pain interfere with work around the home?".

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has 1 location
Recruiting
Research Building BTallahassee, United StatesSee the location
Recruiting
One Study Center