Recruiting soon

Origin Intubation System for Improved Airway Management

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Origin Intubation System

Device
Who is being recruted

From 18 to 75 Years
See all eligibility criteria
How is the trial designed

Device Feasibility Study

Early Phase 1
Interventional
Study Start: October 2025
See protocol details

Summary

Principal SponsorStanford University
Study ContactDr. Amit SaxenaMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: October 1, 2025

Actual date on which the first participant was enrolled.

The study is focused on testing a new medical device called the Origin Intubation System, designed to help doctors manage patients' airways more easily during procedures that require intubation, which is the process of inserting a tube into a person's airway to help them breathe. This system uses a special design inspired by how vines grow, allowing a soft tube to extend and navigate through the airway using low air pressure. This innovative approach aims to make intubation less traumatic and quicker by reducing the need for doctors to have an advanced knowledge of anatomy and by lessening the reliance on visualization tools, which can be challenging to use in complex situations. The study targets healthcare providers who perform intubation, aiming to improve patient care by making the process more efficient and accessible. The study involves using the Origin Intubation System on patients who need intubation. Participants in the study will experience the device's semi-self-navigation capabilities, which means the tube can guide itself with minimal manual intervention, potentially making the process smoother and faster. Researchers will evaluate how well the device works, focusing on its ability to safely and effectively place the tube in the airway. The study is interventional, meaning it involves actively testing the device on patients, and is in the early stages of research. The primary goal is to determine how feasible and effective this new technology is in real-world medical settings, though specific outcome measures are not detailed in this description.

Official TitleClinical Evaluation of the Origin Intubation System 
Principal SponsorStanford University
Study ContactDr. Amit SaxenaMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

15 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Device Feasibility Study

These studies test whether a new medical device (like a tool or piece of equipment) is safe and practical to use. They're usually small and focus on how the device works rather than how well it treats a condition.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Inclusion Criteria: 1. Male or Female subjects 18 years of age or older and less than 75. 2. English or Spanish Speaking. 3. Undergoing elective surgery requiring endotracheal intubation. 4. Use of general anesthesia. Exclusion Criteria: 1. Patients with high aspiration risk. 2. Inability to provide informed consent in English or Spanish 3. Patients for whom an awake intubation is indicated and planned. 4. Patients with a history of head and neck radiation. 5. Pregnant patients. 6. Patients with BMI \>35 7. ASA 4 or higher 8. Patients who the investigator deems ineligible at the investigator's discretion. 9. Planned post-operative intubation. 10. Current incarceration.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
The Origin Intubation System will be utilized on participants undergoing general anesthesia for surgery.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Stanford University

Stanford, United StatesSee the location
Recruiting soonOne Study Center