Recruiting

PRONTO-HNProactive Care Coordination for Head and Neck Cancer Surgery

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What is being tested

Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO)

Other
Who is being recruted

Squamous Cell Carcinoma of Head and Neck+8

+ Carcinoma

+ Carcinoma, Squamous Cell

Over 18 Years
+8 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Services Research Study

Interventional
Study Start: August 2025
See protocol details

Summary

Principal SponsorCentre hospitalier de l'Université de Montréal (CHUM)
Study ContactApostolos Christopoulos, MD, MScMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 21, 2025

Actual date on which the first participant was enrolled.

This study focuses on improving the timing of post-surgery treatments for head and neck cancer patients. Often, there are delays in starting radiotherapy after surgery, which can lead to worse health outcomes. The study is exploring whether a new system called PRONTO-HN can help keep these delays to a minimum, ideally under 42 days, at a specific hospital in Montreal. The system sends automated alerts and coordinates tasks among different healthcare providers to ensure timely treatment. By improving the process, the study aims to enhance survival rates and overall outcomes for patients undergoing postoperative care for head and neck cancer. Participants in this study are divided into two groups. The first group includes patients who received care before the new system was implemented, while the second group includes those treated with the new coordination system. The intervention involves automated alerts and risk assessments to help prioritize and coordinate care more efficiently. The study collects data on each patient's demographics and medical history without requiring their consent, as the intervention is administrative. Researchers will analyze the effectiveness of the system by looking at how well it reduces treatment delays and improves patient outcomes. A smaller group of patients is being studied to see if the new system can significantly reduce the number of patients experiencing delays longer than 42 days.

Official TitleProactive Risk-based Optimization & Notifications for Treatment & Outcomes (PRONTO) in Head & Neck Cancer: A Strategy to Reduce Delays From Surgery to Post-Operative Adjuvant Therapy in Head and Neck Cancer
NCT07180901
Principal SponsorCentre hospitalier de l'Université de Montréal (CHUM)
Study ContactApostolos Christopoulos, MD, MScMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

85 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Services Research Study

These studies look at how healthcare is delivered, managed, and organized. They aim to improve care quality, patient experience, and access to treatment.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Squamous Cell Carcinoma of Head and NeckCarcinomaCarcinoma, Squamous CellHead and Neck NeoplasmsStomatognathic DiseasesMouth DiseasesMouth NeoplasmsNeoplasmsNeoplasms by Histologic TypeNeoplasms by SiteNeoplasms, Glandular and Epithelial

Criteria

6 inclusion criteria required to participate
All adult patients (age 18 or older).

Pathologically confirmed oral cavity or laryngeal squamous cell carcinoma.

Diagnosed from July 2024 to September 2026.

With planned primary intention surgical resection.

Show More Criteria

2 exclusion criteria prevent from participating
Patients who do not end up receiving surgery.

S-PORT > 180 days

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Post-implementation of PRONTO-HN system: 1. Pre-operative risk stratification of requiring adjuvant therapy using our predictive model, applied at tumor board. Patients stratified as fast-track vs normal-track. 2. High-risk patients receive intensive preoperative and postoperative coordination. Low-risk patients are monitored but escalated rapidly if adverse pathology is detected. This includes: * pre-operative dental consultation for fast-track * pre-operative oncology consultation for fast-track with high-risk features * target pathology results 14 days post-operatively for fast-track 3. Automated reminders and target dates sent to members of the multidisciplinary team.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Centre Hospitalier de l'Université de Montréal

Montreal, CanadaOpen Centre Hospitalier de l'Université de Montréal in Google Maps
Recruiting
One Study Center