Titania Nanoparticle Fluoride Varnish for Orthodontic Patients
Fluoride varnish
+ Novel titania nanoparticle infused fluoride varnish
Prevention Study
Summary
Study start date: November 1, 2025
Actual date on which the first participant was enrolled.This study is focused on finding out which type of fluoride varnish is better at preventing plaque buildup in patients with fixed orthodontic braces. Researchers are comparing a new type of fluoride varnish that includes titania nanoparticles made from moringa oleifera leaves to the traditional fluoride varnish. The goal is to see if the nanoparticle-infused varnish can better prevent the biofilm that causes plaque, which is important for maintaining good oral health and avoiding complications like cavities or gum disease in people with braces. Participants in the study will have either the new titania nanoparticle-infused fluoride varnish or the conventional fluoride varnish applied to their teeth. The study is structured in such a way that neither the participants nor the researchers will know which type of varnish each participant receives, ensuring unbiased results. The effectiveness of each varnish will be measured by observing the amount of plaque or biofilm that forms over time. This study seeks to provide valuable insights into improving dental care for orthodontic patients.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.20 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Prevention Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 16 to 30 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Pakistan Institute of Medical Sciences
Islamabad, PakistanOpen Pakistan Institute of Medical Sciences in Google Maps