METAB-BELGROWMetabolic Outcomes in Belgian Children with Growth Hormone Deficiency
metabolic and auxological outcomes
Bone Diseases+10
+ Bone Diseases, Developmental
+ Bone Diseases, Endocrine
Other Study
Summary
Study start date: March 1, 2026
Actual date on which the first participant was enrolled.The study focuses on Belgian children who have a condition called growth hormone deficiency (GHD), which affects their growth and development. The goal is to understand how different types of growth hormone treatments impact the children's metabolism over three years. Some children will receive daily doses of recombinant human growth hormone (rhGH), while others will be treated with a long-acting form given weekly. The research aims to compare these two treatment methods to see which one might offer better outcomes in terms of metabolic health. This study is important as it could help determine the most effective treatment approach for children with GHD, potentially leading to better growth and health. Participants in the study will attend regular follow-up visits every 6 to 12 months, where various health parameters will be recorded. These include clinical assessments, measurements of growth, and biological tests. Additional tests will check for metabolic markers and other health indicators. In some cases, more detailed examinations like DEXA scans to look at body fat and tests to measure the thickness of artery walls will be conducted. These assessments will help researchers understand the effects of the treatments on the children's overall health and growth. The study will also monitor any potential risks or side effects of the treatments.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.300 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Other Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 5 to 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Group II
Study Objectives
Primary Objectives
Secondary Objectives