Completed

Risk Factors for Catheter-Related Infections in Intestinal Failure Patients

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What is being collected

Data Collection

Collected from past medical records and data - Retrospective
Who is being recruted

Intestinal Failure+1

+ Digestive System Diseases

+ Gastrointestinal Diseases

+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
Study Start: January 2025
See protocol details

Summary

Principal SponsorJinling Hospital, China
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on understanding what increases the risk of catheter-related bloodstream infections in people who are hospitalized due to intestinal failure, which affects the body's ability to digest and absorb nutrients. It involves examining patients with different types of intestinal failure to find out which specific factors contribute to these infections. Recognizing these risk factors is important because it can help improve the care and treatment of these patients by preventing infections, which are serious and can lead to longer hospital stays and increased healthcare costs. The study reviews past medical records of 321 patients who had a total of 9,365 days with catheters in place. Researchers use statistical methods to find which factors are independently associated with a higher risk of infection. They also look at how different types of intestinal failure might affect these risks. By analyzing the data, the study aims to suggest better prevention strategies tailored to each subtype and to emphasize the importance of monitoring patients' metabolic and immune systems closely while they are hospitalized.

Official TitleSubtype-Specific Catheter-Related Bloodstream Infection Risk Factors in Hospitalized Patients With Intestinal Failure: A Retrospective Study
NCT07172711
Principal SponsorJinling Hospital, China
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

321 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Intestinal FailureDigestive System DiseasesGastrointestinal DiseasesIntestinal Diseases

Criteria

1 inclusion criteria required to participate
Patients meeting the ESPEN 2023 diagnostic criteria for intestinal failure.

1 exclusion criteria prevent from participating
Catheter indwelling duration <48 hours; Implanted catheter before admission; Complex components in PN difficult to quantify; Positive blood cultures with unclear CRBSI diagnosis; Alternative infection sources identified.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Jinling Hospital

Nanjing, ChinaOpen Jinling Hospital in Google Maps
CompletedOne Study Center