Recruiting

Postoperative Rehabilitation Timing for Lumbar Disc Herniation

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What is being tested

Standardized Postoperative Rehabilitation Protocol

Behavioral
Who is being recruted

Bone Diseases+4

+ Hernia

+ Intervertebral Disc Displacement

From 19 to 65 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2025
See protocol details

Summary

Principal SponsorLi Xiang
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 28, 2025

Actual date on which the first participant was enrolled.

This study focuses on understanding how the timing of rehabilitation after spine surgery affects recovery outcomes for patients with lumbar disc herniation, a condition where the soft cushioning between the bones in the spine bulges out. The research specifically looks at patients who have undergone a particular type of spine surgery known as unilateral biportal endoscopic (UBE) spine surgery. By determining whether starting rehabilitation sooner or later after surgery makes a difference, the study aims to provide valuable information that can help doctors make better treatment decisions and improve patient care. Participants in this study are divided into two groups. One group begins rehabilitation exercises two weeks after their surgery, while the other group starts six weeks after. The study collects and analyzes data from both groups before surgery, immediately after surgery, and over a year-long follow-up period. The focus is on comparing the recovery outcomes of the two groups to see which timing leads to better results. By doing so, the study hopes to find the best rehabilitation schedule to enhance recovery in patients who have had this specific spine surgery.

Official TitleThe Influence of the Timing of Postoperative Rehabilitation Intervention on the Clinical
NCT07161232
Principal SponsorLi Xiang
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

72 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 19 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Bone DiseasesHerniaIntervertebral Disc DisplacementMusculoskeletal DiseasesSpinal DiseasesPathological Conditions, Signs and SymptomsPathological Conditions, Anatomical

Criteria

Inclusion Criteria: * Aged between 19 and 65 years. Diagnosed with lumbar disc herniation by imaging and scheduled for unilateral biportal endoscopic (UBE) surgery. Presenting with radicular pain in the lower extremity, with a history of less than 1 year. Able to understand Chinese and complete questionnaires independently. Physically capable of participating in exercise rehabilitation. Willing to participate and provide written informed consent. Exclusion Criteria: * Aged under 18 or over 65 years. Combined with other spinal pathologies (e.g., ankylosing spondylitis, rheumatoid arthritis, spinal tumor, spinal fracture, cauda equina syndrome). Diagnosis of neurological disorders (e.g., multiple sclerosis, Parkinson's disease). Presence of uncontrolled cardiovascular, respiratory, or peripheral vascular diseases. History of severe psychiatric disorders (e.g., schizophrenia). Previous history of spinal surgery. Pregnancy or lactation. Inability to understand or comply with the study procedures.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Patients in this arm will commence a standardized, progressive rehabilitation program at 2 weeks (±3 days) following unilateral biportal endoscopic (UBE) surgery. The regimen consists of core stability exercises and neurodynamic techniques designed to early activate core muscles, prevent neural adhesion, and restore function. Specific exercises include transverse abdominis activation, sit-to-stand training with abdominal bracing, four-point kneeling rockbacks for spinal mobility, neural mobilization in the modified straight leg raise position, and neural sliding techniques. The exercises are performed once daily and progressed based on patient tolerance. The entire intervention is supervised by a senior physical therapist.

Group II

Active Comparator
This arm serves as the active comparator. Patients will commence the identical standardized, progressive rehabilitation program as the Experimental arm at 6 weeks (±3 days) following unilateral biportal endoscopic (UBE) surgery. The content of the rehabilitation regimen, exercise frequency, progression criteria, and supervision by a physical therapist are exactly the same as in the Experimental arm. This timing represents the conventional, later postoperative rehabilitation approach.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Beijing Friendship Hospital

Beijing, ChinaOpen Beijing Friendship Hospital in Google Maps
Recruiting
One Study Center