BIND Score for Severe Neonatal Jaundice in NICU
This study aims to observe and assess the usefulness of the BIND score in evaluating severe neonatal jaundice in newborns admitted to the neonatal intensive care unit.
Data Collection
Collected from today forward - ProspectiveHyperbilirubinemia+3
+ Infant, Newborn, Diseases
+ Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Summary
Study start date: October 1, 2025
Actual date on which the first participant was enrolled.This study focuses on evaluating the effectiveness of the BIND score in predicting and diagnosing severe jaundice in newborns who are in the neonatal intensive care unit (NICU). Severe jaundice can lead to serious conditions such as neonatal encephalopathy, which affects the baby's brain. The goal is to find out if using the BIND score can help detect these issues early, allowing for timely treatment and potentially preventing further complications. This study is crucial because early intervention could improve outcomes for newborns with high bilirubin levels, which is the substance that causes jaundice. Participants in this study will have their neurological condition assessed using the BIND score, a tool that helps evaluate the severity of jaundice-related brain issues. Following this assessment, phototherapy, a common treatment for reducing bilirubin levels, will be administered. The study will measure how well the BIND score predicts the need for such treatment and its overall effectiveness in managing jaundice. By determining the BIND score's predictive and diagnostic value, the study aims to enhance the care provided to newborns with severe jaundice, ultimately reducing the risk of brain damage.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.80 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Conditions
Pathology
Criteria
Inclusion criteria: Newborn \< 28 days old Neonates with severe hyperbilirubinemia need extensive phototherapy impending exchange transfusion Exclusion criteria: Age \> 28 days old Neonates with any abnormal neurological signs suggesting neurological disease (hypoxic ischemic encephalopathy, muscle disease, …etc.).
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives