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BIND Score for Severe Neonatal Jaundice in NICU

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Study Aim

This study aims to observe and assess the usefulness of the BIND score in evaluating severe neonatal jaundice in newborns admitted to the neonatal intensive care unit.

What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Hyperbilirubinemia+3

+ Infant, Newborn, Diseases

+ Congenital, Hereditary, and Neonatal Diseases and Abnormalities

See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: October 2025
See protocol details

Summary

Principal SponsorAssiut University
Study ContactNouralhoda Ahmed Metwally
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on evaluating the effectiveness of the BIND score in predicting and diagnosing severe jaundice in newborns who are in the neonatal intensive care unit (NICU). Severe jaundice can lead to serious conditions such as neonatal encephalopathy, which affects the baby's brain. The goal is to find out if using the BIND score can help detect these issues early, allowing for timely treatment and potentially preventing further complications. This study is crucial because early intervention could improve outcomes for newborns with high bilirubin levels, which is the substance that causes jaundice. Participants in this study will have their neurological condition assessed using the BIND score, a tool that helps evaluate the severity of jaundice-related brain issues. Following this assessment, phototherapy, a common treatment for reducing bilirubin levels, will be administered. The study will measure how well the BIND score predicts the need for such treatment and its overall effectiveness in managing jaundice. By determining the BIND score's predictive and diagnostic value, the study aims to enhance the care provided to newborns with severe jaundice, ultimately reducing the risk of brain damage.

Official TitlePredictive and Diagnostic Value of BIND Score in Assessment of Severe Neonatal Jaundice Cases in NICU
NCT07150494
Principal SponsorAssiut University
Study ContactNouralhoda Ahmed Metwally
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

80 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Range of ages for which participants are eligible to join.

Conditions

Pathology

HyperbilirubinemiaInfant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesPathologic ProcessesPathological Conditions, Signs and SymptomsHyperbilirubinemia, Neonatal

Criteria

Inclusion criteria: Newborn \< 28 days old Neonates with severe hyperbilirubinemia need extensive phototherapy impending exchange transfusion Exclusion criteria: Age \> 28 days old Neonates with any abnormal neurological signs suggesting neurological disease (hypoxic ischemic encephalopathy, muscle disease, …etc.).

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
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