Recruiting

Suprachoroidal Triamcinolone for Macular Edema in Resistant Non-Infectious Uveitis

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What is being tested

Suprachoroidal triamcinolone acetonide injection

Drug
Who is being recruted

Eye Diseases+2

+ Macular Degeneration

+ Macular Edema

Over 18 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Early Phase 1
Interventional
Study Start: September 2024
See protocol details

Summary

Principal SponsorUniversity of Baghdad
Study ContactMohammed Suhail Al-Salam
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: September 1, 2024

Actual date on which the first participant was enrolled.

This study investigates a new treatment option for people with a specific type of eye inflammation, known as non-infectious uveitis, which leads to swelling in the central part of the retina (called macular edema). The swelling can threaten vision and is particularly challenging to treat in patients who haven't responded to the usual steroid injections around the eye. The study aims to determine if injecting a medicine called triamcinolone directly into a part of the eye called the suprachoroidal space can help reduce the swelling and improve vision. This approach could provide a new treatment possibility for those who haven't found relief with existing methods. Participants in the study will first undergo an assessment that includes a vision test and an eye examination involving a special scan called OCT to evaluate the retina. They will then receive a single injection of triamcinolone into the suprachoroidal space of the eye. This procedure is done with numbing drops in a sterile environment similar to an operating room. The participants will return for follow-up visits one month and three months after the injection to check their vision and retina through repeat tests and scans. They are advised to monitor for any signs of complications, such as pain, redness, or changes in vision, and to contact the clinic if these occur.

Official TitleSuprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon
NCT07145008
Principal SponsorUniversity of Baghdad
Study ContactMohammed Suhail Al-Salam
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

20 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Eye DiseasesMacular DegenerationMacular EdemaRetinal DegenerationRetinal Diseases

Criteria

4 inclusion criteria required to participate
Non-infectious uveitis complicated with macular edema

Uveitic macular edema of less than four months' duration

Macular edema persisted despite lack of intra-ocular inflammation

No response to posterior sub-Tenon triamcinolone acetonide injections

2 exclusion criteria prevent from participating
Those with epiretinal membrane-associated macular edema

Below 18 years

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Ibn Al-Haitham Eye Teaching Hospital

Baghdad, IraqOpen Ibn Al-Haitham Eye Teaching Hospital in Google Maps
Recruiting
One Study Center