HRS-4508 and Anti-tumor Therapy for Solid Tumor
HRS-4508+ Capecitabine
+ HRS-4508+ Trastuzumab
+ HRS-4508+ Trastuzumab+ Pertuzumab
Treatment Study
Summary
Study start date: October 1, 2025
Actual date on which the first participant was enrolled.This clinical trial is exploring a new treatment option for people with solid tumors, which are abnormal masses of tissue that can occur in various organs. The study aims to determine how effective and safe a combination of different anti-cancer therapies, including a new drug called HRS-4508, is for these patients. This research is crucial because finding a more effective treatment could significantly improve outcomes for individuals with these types of cancers, which are often challenging to treat with existing options. Participants in the study will receive HRS-4508 along with other cancer treatments, and their response to the treatment will be closely monitored. Researchers will measure how well the tumors respond using specific criteria and will also keep track of any side effects experienced. By understanding the best dosage and potential adverse reactions, the study aims to establish a safe and effective treatment regimen. The study also examines how the body absorbs, distributes, and processes HRS-4508 and other drugs used in the combination, providing comprehensive data on their behavior within the body.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.120 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 75 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.6 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalGroup III
ExperimentalGroup IV
ExperimentalGroup 5
ExperimentalGroup 6
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Cancer Hospital Chinese Academy of Medical Science
Beijing, ChinaOpen Cancer Hospital Chinese Academy of Medical Science in Google Maps