Completed

FrozenShoulderCentral Sensitization Impact on Shoulder Adhesive Capsulitis Treatment

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Bursitis+5

+ Joint Diseases

+ Musculoskeletal Diseases

From 18 to 80 Years
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
Study Start: January 2021
See protocol details

Summary

Principal SponsorAnkara City Hospital Bilkent
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2021

Actual date on which the first participant was enrolled.

Adhesive capsulitis, commonly known as frozen shoulder, causes chronic shoulder pain and affects daily activities. This study focuses on understanding how a condition called central sensitization, which amplifies pain signals in the central nervous system, influences the effectiveness of treatments for adhesive capsulitis. Central sensitization can make treatment challenging and reduce its success. The study includes 32 participants who have adhesive capsulitis, some of whom also have central sensitization. The aim is to determine if the presence of central sensitization affects the outcomes of physical therapy and exercise treatments. Understanding this relationship could improve treatment strategies and provide better relief for those suffering from prolonged shoulder pain. Participants receive conventional physical therapy and exercise treatments. Their progress is measured using several scales: the Visual Analog Scale (VAS) to assess pain severity, the Shoulder Pain and Disability Index (SPADI) to evaluate shoulder pain and disability, and the Tampa Kinesiophobia Scale (TKS) and Pain Catastrophizing Scale (PCS) to consider psychological factors related to pain. Additionally, shoulder range of motion is measured at three different times: before treatment, immediately after treatment, and two weeks post-treatment. These measurements help determine the effectiveness of the treatments and whether central sensitization affects recovery. The study could identify specific needs for those with central sensitization, leading to more tailored treatment approaches.

Official TitleEffects of Central Sensitization Presence on the Results of Shoulder Adhesive Capsulitis Treatment With Physical Therapy Agents and Exercise
NCT07131839
Principal SponsorAnkara City Hospital Bilkent
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

32 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BursitisJoint DiseasesMusculoskeletal DiseasesNeurologic ManifestationsPainSigns and SymptomsPathological Conditions, Signs and SymptomsChronic Pain

Criteria

Inclusion Criteria: 1)patients with adhesive capsulitis between 18-80 years old 2) symptoms ongoing more than 3 months 3) willing to participated in the study Exclusion Criteria: 1\) patients with cervical radiculopathy 2) Patients with predisposing factors to adhesive capsulitis, such as diabetes mellitus, thyroid disease, coronary artery disease, lung pathologies or tuberculosis 3) any defined central sensitization syndrome such as fibromiyalgia before 4) presence of rheumatologic diseases 5) pregnancy 6) patients underwent bypass surgery or who have cardiac pacemaker 7) patients with septic arthritis or sepsis 8) malignancy 9) patients that underwent surgery through the shoulder region or had injection through the shoulder joint in the last 3 months. \-

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)Open Ankara Bilkent City Hospital in Google Maps
CompletedOne Study Center