Gastrointestinal Bleeding Risk in Ischemic Heart Disease on Antiplatelet Therapy
Data Collection
Collected from past medical records and data - RetrospectiveArterial Occlusive Diseases+11
+ Arteriosclerosis
+ Cardiovascular Diseases
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Summary
Study start date: September 1, 2025
Actual date on which the first participant was enrolled.This clinical study focuses on patients with ischemic heart disease, a condition where blood flow to the heart is restricted due to narrowed or blocked arteries. The study aims to understand the frequency and risk of gastrointestinal bleeding, which is bleeding within the digestive system, in patients who are treated with either single or dual antiplatelet therapy. Antiplatelet medications like aspirin and clopidogrel are used to prevent blood clots and reduce heart attack risk, but they can also increase the chance of bleeding in the digestive tract. The study seeks to find ways to minimize these bleeding risks while maintaining the effectiveness of heart disease treatment. Participants in this study are observed to compare the rates of gastrointestinal bleeding between those on single antiplatelet therapy and those on dual therapy. The study is observational, meaning it does not involve any experimental treatment; instead, it monitors patients' health outcomes under their current medication regimens. Researchers measure the occurrence of bleeding events, looking at whether the use of one or two antiplatelet drugs affects the likelihood of bleeding complications. The ultimate goal is to identify safer treatment strategies for managing heart disease without increasing the risk of gastrointestinal issues.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.112 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives