Recruiting

Digital Pancreaticobiliary Scope for Biliary Disorders

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What is being tested

Dragonfly™ Digital Pancreaticobiliary System

Device
Who is being recruted

Adenocarcinoma+3

+ Carcinoma

+ Neoplasms

Over 21 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Phase 4
Interventional
Study Start: August 2025
See protocol details

Summary

Principal SponsorUniversity of Colorado, Denver
Study ContactRodolfo Hernandez
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: August 11, 2025

Actual date on which the first participant was enrolled.

This study focuses on evaluating a new tool called the Dragonfly™ Pancreaticobiliary Scope, designed for people with bile duct problems like stones or strictures. Up to 75 participants with these conditions will be part of the research. The goal is to see if this scope works well in breaking down tough bile duct stones and in gathering tissue samples for analysis. The study aims to improve the effectiveness of endoscopy procedures for these issues, potentially leading to better patient outcomes and less invasive treatments. Participants undergoing a scheduled endoscopy will use the Dragonfly™ Scope along with its accessories to treat their bile duct condition. The scope's ability to fragment stones and collect tissue samples will be closely monitored. Endoscopists will also evaluate the product's performance, focusing on how easy it is to use and how well it functions during procedures. This feedback is crucial in determining the scope's effectiveness and in making any necessary adjustments for future use.

Official TitleProspective Multicenter Clinical Performance Study of a Single-use Large Channel Digital Pancreaticobiliary Scope (DPS) With Compatible Accessories 
NCT07120295
Principal SponsorUniversity of Colorado, Denver
Study ContactRodolfo Hernandez
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

75 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 21 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

AdenocarcinomaCarcinomaNeoplasmsNeoplasms by Histologic TypeNeoplasms, Glandular and EpithelialCholangiocarcinoma

Criteria

Inclusion Criteria: 1. Provision to sign and date the consent form; 2. Adult patients ≥ 21 years old; 3. Any patient who is required to undergo endoscopic retrograde cholangiopancreatography (ERCP) procedure with the clinical need to perform cholangioscopy for: 1. Indeterminate biliary stricture, or 2. Failed biliary stone extraction with conventional techniques. 4. Willing and able to follow study procedures and comply with study follow-up. Exclusion Criteria: 1. Pregnancy or lactation; 2. Surgically or physiologically altered GI anatomy that precludes advancement of the duodenoscope for biliary cannulation; 3. Patients on anti-coagulants and anti-platelet medications that cannot be withheld pre-procedure, except for aspirin, 81mg; 4. Coagulopathy (INR \> 1.8) or thrombocytopenia (Platelets \< 50,000) that is not correctable and felt to be a contraindication to proceeding with biopsy or lithotripsy per the treating endoscopist; 5. Active suppurative cholangitis with evidence of purulent drainage at the time of papilla visualization; 6. Patients who are not candidates for anesthesia to permit ERCP.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Universtiy of Colorado Hospital

Aurora, United StatesSee the location
Recruiting
One Study Center