uveitisAnkylosing Spondylitis-Associated Uveitis Characteristics in Egyptian Patients
Data Collection
Collected from past medical records and data - RetrospectiveAxial Spondyloarthritis+11
+ Ankylosis
+ Arthritis
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Summary
Study start date: September 1, 2023
Actual date on which the first participant was enrolled.This study focuses on understanding the eye condition known as Anterior Uveitis that occurs in patients with Ankylosing Spondylitis, a type of arthritis that affects the spine. Conducted in Egypt, it looks at how this eye problem presents itself in Egyptian patients and aims to identify factors that influence their vision outcomes. By focusing on this specific group, the study seeks to provide insights that could help improve diagnosis and treatment plans for people with similar conditions, potentially leading to better management of their symptoms and overall quality of life. Participants in this study include Egyptian patients diagnosed with Ankylosing Spondylitis who also experience anterior uveitis. The study involves reviewing their medical records to track changes in their vision, specifically using a scale called the logMAR to measure their Corrected Distance Visual Acuity (CDVA). This measurement is taken when they first visit the clinic and again after an average of three months of treatment. The study evaluates how these changes relate to the clinical characteristics and treatments they receive, as well as any complications that arise.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.22 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: * Egyptian nationality. Age: ≥ 18 years. Confirmed diagnosis of Ankylosing Spondylitis (AS) according to the Modified New York Criteria, including: Clinical symptoms (e.g., chronic inflammatory back pain, reduced lumbar motion, reduced chest expansion) Radiographic evidence of sacroiliitis. Confirmed diagnosis of Acute Anterior Uveitis (AAU) based on: Ophthalmologic examination (e.g., slit-lamp biomicroscopy) Ancillary testing (e.g., Optical Coherence Tomography \[OCT\] and/or Fluorescein Angiography \[FA\]). Presentation to the Spine Clinic of Benha University - Faculty of Medicine between September 2023 and August 2024 with ophthalmic complaints, subsequently referred to the Ophthalmology Clinic. Complete medical and ophthalmologic records available. Received treatment for both AS and AAU. At least one follow-up visit after initiation of treatment. Exclusion Criteria: * Non-Egyptian patients. History of other systemic autoimmune or immunological diseases (e.g., sarcoidosis, Behçet's disease, systemic lupus erythematosus). Uveitis due to non-autoimmune secondary causes (e.g., infectious uveitis, trauma-related uveitis). History of ocular surgery prior to the episode of AAU
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location