Recruiting

Electronic Health Record Alert on PSA Screening Rates

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Annual PSA Health Maintenance Reminder

Other
Who is being recruted

Urogenital Diseases+7

+ Genital Diseases

+ Genital Diseases, Male

From 40 to 75 Years
See all eligibility criteria
How is the trial designed

Services Research Study

Interventional
Study Start: August 2025
See protocol details

Summary

Principal SponsorWashington University School of Medicine
Study ContactLannis Hall, M.D., MPH
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: August 11, 2025

Actual date on which the first participant was enrolled.

This clinical trial aims to examine how using electronic health record alerts can influence the rates of PSA screening, a test for prostate cancer, across a network of ten hospitals. The focus is on encouraging annual discussions between healthcare providers and patients about PSA screening, using technology to support decisions based on the latest guidelines for prostate cancer risk. This study is important because it seeks to catch prostate cancer early while reducing unnecessary diagnoses, thereby improving patient care by ensuring that screenings are both available and effective. Participants in the study will engage in shared decision-making conversations guided by enhanced clinical decision support tools. These tools help standardize how healthcare providers decide on and refer patients for PSA screening, based on clinical guidelines. The study evaluates the effectiveness of these tools in reducing differences in how providers screen for prostate cancer and in ensuring that the screenings align with recommended practices. By doing so, the study hopes to find a balance between catching cancer early and avoiding unneeded treatments.

Official TitleImpact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System 
NCT07109427
Principal SponsorWashington University School of Medicine
Study ContactLannis Hall, M.D., MPH
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

40000 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Services Research Study

These studies look at how healthcare is delivered, managed, and organized. They aim to improve care quality, patient experience, and access to treatment.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 40 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesGenital DiseasesGenital Diseases, MaleGenital Neoplasms, MaleNeoplasmsNeoplasms by SiteProstatic DiseasesProstatic NeoplasmsUrogenital NeoplasmsMale Urogenital Diseases

Criteria

Eligibility Criteria: * Receive care within the BJC Health System * Have had at least one primary care physician appointment in the calendar year of PSA screening (primary care) * Be male * Not have a history of prostate cancer * Meet one of the following risk criteria: * High Risk for Prostate Cancer * African American, between the ages of 40 and 75 (inclusive), or * Family history of prostate, breast, ovarian, and/or pancreatic cancer, or * Known familial germline mutation OR * Average Risk for Prostate Cancer * Between the ages of 50 and 75 (inclusive)

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
An annual health maintenance reminder will be implemented for all men who meet the American Cancer Society guidelines for average- and high-risk eligibility criteria. The goal is to encourage their primary care provider (PCP) to engage in a shared decision-making discussion with the patient about the benefits and risks of prostate cancer screening. This alert will appear in the health maintenance reminder section of the electronic health record (EHR). Although all providers with access to EPIC can view the alert, it is typically the PCPs who review and take action on alerts in the health maintenance reminder section.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Washington University School of Medicine

Saint Louis, United StatesSee the location
Recruiting
One Study Center