Amniotic Tissue for Biliary Outcomes in Living Donor Liver Transplant

This study focuses on using placental tissue grafts in adult patients who receive a liver transplant from a living donor. The main aim is to see if these grafts, specifically the MiMedx placental tissue grafts, can safely reduce complications related to bile ducts, which are crucial for liver function. Bile duct problems are a common issue after liver transplants, and finding a way to reduce these could significantly improve patient outcomes. This is important because it can enhance the healing process and overall success of liver transplants. Participants in this study undergo a liver transplant at the Cleveland Clinic as per standard procedures. During the surgery, a MiMedx placental tissue graft is placed around the bile duct connection. After the transplant, doctors regularly check the patients for a year to see if any bile duct complications arise. The study involves reviewing the participants’ medical records during follow-up visits to track progress and outcomes. This helps researchers understand the effectiveness of the grafts in preventing complications.