Compare Additively vs Subtractively Manufactured Implant Supported Fixed Dental Prostheses
This study compares the clinical success of additively and subtractively manufactured implant-supported fixed dental prostheses, focusing on the absence of complications over the observation period.
AM manufacturing method
+ SM manufacturing method
Treatment Study
Summary
Study start date: July 30, 2025
Actual date on which the first participant was enrolled.This clinical trial aims to compare two different ways of making dental crowns for patients who need a strong and permanent crown on the back teeth. The study involves patients who will receive implant-supported crowns made either by adding materials layer by layer (additive manufacturing) or by cutting away from a solid block (subtractive manufacturing). The trial takes place at Harvard School of Dental Medicine and the University of Zurich's Center of Dental Medicine. Understanding which method results in better crowns could improve dental treatments and outcomes for patients requiring such dental implants. Participants in the study receive a single implant-supported crown created by one of the two methods, depending on their group assignment. After receiving their crowns, participants are monitored for three years to evaluate how well the crowns perform. The study checks the crowns' clinical performance, including their technical, biological, and aesthetic aspects. Both the dental technicians and patients will report their outcomes, ensuring a comprehensive assessment of the crowns' effectiveness and satisfaction. This research could highlight significant differences in durability and patient satisfaction between the two manufacturing methods.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.50 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 20 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
Active ComparatorStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 2 locations
Harvard School of Dental Medicine
Boston, United StatesOpen Harvard School of Dental Medicine in Google MapsCenter of Dental Medicine, University of Zurich
Zurich, Switzerland