Recruiting

Plantaris SxTargeting Plantaris Muscle-tendon Unit in Ankle Equinus Surgical Correction for Children

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
Study Aim

This study examines the impact of targeting the Plantaris muscle-tendon unit in surgical correction of ankle equinus in children, measuring ankle dorsiflexion during surgery.

What is being tested

Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy

+ Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession

Procedure
Who is being recruted

Congenital Abnormalities+25

+ Brain Injuries, Traumatic

+ Brain Damage, Chronic

From 4 to 17 Years
+12 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2023
See protocol details

Summary

Principal SponsorUniversity of Alberta
Study ContactAilar Ramadi, PhDMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Study start date: March 13, 2023

Actual date on which the first participant was enrolled.

This study focuses on children who have a walking condition known as equinus gait, where the ability to flex the ankle upwards is reduced, often leading to walking on the toes. This condition can be linked to various causes such as cerebral palsy or idiopathic toe-walking. The study aims to explore how the plantaris muscle might be contributing to this issue. By understanding this, the study hopes to improve surgical methods used to correct ankle equinus, potentially allowing for less invasive surgeries and faster recovery times for children affected by this condition. In the study, children undergoing surgery for equinus contracture at the Stollery Children's Hospital will be randomly assigned to one of two groups. One group will have the plantaris tendon addressed before other muscle lengthening procedures, while the second group will have it addressed after. Surgeons will measure the range of motion in the ankle at different stages during the surgery to evaluate the impact of the plantaris tendon on ankle movement. This careful measurement aims to determine if addressing the plantaris muscle first can improve surgical outcomes and reduce the need for more extensive procedures, making recovery easier for young patients.

Official TitleThe Effect of Targeting the Plantaris Muscle-tendon Unit in Surgical Correction of Ankle Equinus in Children 
NCT07090057
Principal SponsorUniversity of Alberta
Study ContactAilar Ramadi, PhDMore contacts
Last updated: December 11, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

42 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 4 to 17 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Congenital AbnormalitiesBrain Injuries, TraumaticBrain Damage, ChronicBrain DiseasesBrain InjuriesCardiovascular DiseasesCentral Nervous System DiseasesCerebral PalsyCerebrovascular DisordersCharcot-Marie-Tooth DiseaseCraniocerebral TraumaCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNervous System MalformationsNervous System DiseasesNeuromuscular DiseasesPeripheral Nervous System DiseasesPolyneuropathiesSpinal Cord DiseasesSpinal Cord InjuriesVascular DiseasesWounds and InjuriesHereditary Sensory and Motor NeuropathySpastic Paraplegia, HereditaryNeurodegenerative DiseasesTrauma, Nervous SystemHeredodegenerative Disorders, Nervous SystemStrokeGenetic Diseases, Inborn

Criteria

5 inclusion criteria required to participate
Known underlying diagnosis of any of the following: idiopathic toe walking, cerebral palsy, hereditary spastic paraparesis, traumatic brain injury, spinal cord injury/tethering, hereditary sensory-motor neuropathy, stroke

Pediatric patients (4-17 years) who have consented for surgery for the management of equinus contracture \* (either TA lengthening or GN recession) at the Stollery Children's Hospital

Passive plantarflexion on affected side greater than 20° and greater than degree of equinus contracture. * Note: may be isolated or in conjunction with other orthopaedic procedures; in bilateral ankle equinus procedures, data will be collected bilaterally, but included as a single participant (i.e., single randomization).

Ability to provided informed consent/assent in English.

Show More Criteria

7 exclusion criteria prevent from participating
Known or suspected arthrofibrosis.

Knee flexion contracture of greater than 5°

BoNTA injections below the affected knee within the last six months

Unable to provide informed consent/assent in English.

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Participants undergo Tendoachilles (TA) lengthening or gastrocnemius (GN) recession surgery before Plantaris tenotomy.

Group II

Experimental
Participants undergo Plantaris tenotomy surgery before Tendoachilles (TA) lengthening or gastrocnemius (GN) recession.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Stollery Children's Hospital

Edmonton, CanadaSee the location
Recruiting
One Study Center