Recruiting soon
ACPS

Adaptive Cell Phone Support for Medication Adherence in Adolescents and Young Adults with Chronic Conditions

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Adaptive Cell Phone Support

Behavioral
Who is being recruted

Medication Adherence

From 15 to 20 Years

See all eligibility criteria

How is the trial designed

Supportive Care Study

Interventional
Study Start: February 2026

See protocol details

Summary

Principal SponsorChildren's Hospital Los Angeles
Study ContactCaitlin Sayegh, PhD
Last updated: July 24, 2025
Sourced from a government-validated database.Claim as a partner
Study start date: February 1, 2026Actual date on which the first participant was enrolled.

This study is designed to explore ways to help adolescents and young adults with chronic health conditions stick to their medication plans. Participants will use a new cell phone-based support system for three weeks. The main aim is to gather their feedback on how easy and helpful the system is, so it can be improved for future use. This research is important as it seeks to address the challenge of medication adherence, which is a common issue for young people managing long-term health problems. Participants will be enrolled in a trial where they will use the intervention for a set period and then provide feedback on its usability and effectiveness. The study will not involve any new medications or treatments, just the use of a supportive digital tool. Researchers hope to learn what works best in keeping young patients engaged and adherent to their medication schedules. Their feedback will be crucial in shaping the final version of the intervention for future trials.

Official TitleAdaptive Cell Phone Support to Promote Medication Adherence Among Adolescents and Young Adults With Chronic Health Conditions 
Principal SponsorChildren's Hospital Los Angeles
Study ContactCaitlin Sayegh, PhD
Last updated: July 24, 2025
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details
35 patients to be enrolledTotal number of participants that the clinical trial aims to recruit.
Supportive Care Study
These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.

How participants are assigned to different groups/arms
In this clinical study, all participants receive the same treatment. Since there is only one group, there is no need for randomization or assignment to different arms. This type of study is often used to test a new treatment without comparing it to another.

Other Ways to Assign Participants
Randomized allocation: Participants are assigned randomly, like flipping a coin, to ensure fairness and reduce bias.
Non-randomized allocation: Participants are assigned based on specific factors, such as their medical condition or a doctor's decision.

How treatments are given to participants
In this study, all participants receive the same treatment. This approach is often used to evaluate the effects of a single intervention without comparing it to another.

Other Ways to Assign Treatments
Parallel assignment: Participants are split into separate groups, each receiving a different treatment.
Cross-over assignment: Participants switch between treatments during the study.
Factorial assignment: Participants receive different combinations of treatments.
Sequential assignment: Participants receive treatments one after another in a specific order, possibly based on individual responses.
Other assignment: Treatment assignment does not follow a standard or predefined design.

How the effectiveness of the treatment is controlled
In a non placebo-controlled study, no participants receive an inert substance (placebo) to compare outcomes. Instead, all participants receive either the experimental treatment or an alternative treatment (often the Standard of Care). This method allows researchers to compare the effects of the experimental treatment with those of a different active intervention, rather than a placebo.

Other Options
Placebo-Controlled: A placebo is used to compare the effects of the experimental treatment with those of an inert substance, isolating the true treatment effect.

How the interventions assigned to participants is kept confidential
Everyone involved in the study knows which treatment is being given. This is typically used when it's not possible or necessary to hide the treatment details from participants or researchers.

Other Ways to Mask Information
Single-blind: Participants do not know which treatment they are receiving, but researchers do.
Double-blind: Neither participants nor researchers know which treatment is given.
Triple-blind: Participants, researchers, and outcome assessors do not know which treatment is given.
Quadruple-blind: Participants, researchers, outcome assessors, and care providers all do not know which treatment is given.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria
Any sexBiological sex of participants that are eligible to enroll.
From 15 to 20 YearsRange of ages for which participants are eligible to join.
Healthy volunteers not allowedIf individuals who are healthy and do not have the condition being studied can participate.
Conditions
Pathology
Medication Adherence
Criteria

Inclusion Criteria: * Children's Hospital Los Angeles patient * between 15-20 years old * taking at least one oral medication per day for a chronic health condition * English speaking * demonstrating sufficient cognitive capacity to engage in the assent/consent process and study procedures There is no exclusion criteria.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives
One single intervention group 

is designated in this study

This study does not include a placebo group 

Treatment Groups
Group I
Experimental
Computer-delivered cell phone support (reminders, problem-solving, referrals to resources) and responsive human coaching (phone calls, test messages, in-app messaging) to improve medication adherence.
Study Objectives
Primary Objectives

Higher scores indicate a greater "extent to which people delivering or receiving a healthcare intervention consider it to be appropriate, based on anticipated or experienced cognitive and emotional responses to the intervention"; the minimum value of this questionnaire is 7 and the maximum value is 35.

Higher scores indicate greater ease with which users can use technology to achieve a particular goal; the minimum value of this questionnaire is 1 and the maximum value is 7.

Percentage of doses taken our of 100%; higher numbers indicate greater medication adherence. This scale presents participants with a line, marked 0 on the left and 100 on the right, and participants can drag a marker to the place on the line that best visually indicated their adherence.

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has no location dataSave this study to your profile to know when the location data is available. 
Recruiting soonNo study centers