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Pulmonary Arterial Hypertension and Diabetes Impact on Long-term Survival

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What is being collected

Data Collection

Collected from past medical records and data - Retrospective
Who is being recruted

Pulmonary Arterial Hypertension+6

+ Diabetes Mellitus

+ Endocrine System Diseases

From 18 to 80 Years
+4 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Other

Utilizing specific methods not covered by standard models in order to address unique research questions.
Observational
Study Start: August 2025
See protocol details

Summary

Principal SponsorXijing Hospital
Study ContactYue Zhang, Doctor
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on understanding how diabetes affects the long-term survival of people with pulmonary arterial hypertension (PAH), a condition where the blood pressure in the lungs' arteries is higher than normal. By collecting data from at least 5,000 patients across multiple centers, the study aims to compare the survival rates of those with PAH who also have diabetes against those who do not have diabetes. This research is important because it seeks to identify what factors might influence survival rates, potentially leading to better treatment strategies and improved patient care for those with both conditions. In this observational study, researchers will gather existing medical records of patients diagnosed with PAH to analyze survival times and identify any patterns or risk factors that might affect these outcomes. The primary outcome being measured is the overall survival, which is determined by the time from when a patient is diagnosed with PAH until their passing. Since this is a retrospective study, participants do not undergo any new treatments or interventions; instead, the study relies on previously collected data to draw conclusions. The findings could help highlight which specific factors, such as the presence of diabetes, may impact the long-term prognosis of patients with PAH.

Official TitleLong-term Survival and Influencing Factors of Patients With Pulmonary Arterial Hypertension and diabetes-a Multicenter Retrospective Cohort Study
NCT07082933
Principal SponsorXijing Hospital
Study ContactYue Zhang, Doctor
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

5000 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Other

Some studies use unique or mixed approaches that don't fit standard categories. These may include innovative observational methods or studies tailored to specific research questions.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Pulmonary Arterial HypertensionDiabetes MellitusEndocrine System DiseasesHypertension, PulmonaryLung DiseasesMetabolic DiseasesNutritional and Metabolic DiseasesRespiratory Tract DiseasesGlucose Metabolism Disorders

Criteria

2 inclusion criteria required to participate
Individuals aged 18 to 80 years with full capacity for civil conduct.

Patients diagnosed with pulmonary hypertension by community-level and/or higher-level medical institutions.

2 exclusion criteria prevent from participating
Patients with malignant tumors.

Other physical conditions judged by the researchers as making the patients ineligible to participate in the clinical study.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
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