Radiocaine Safety and Dosimetry in Healthy Volunteers

This clinical trial is focused on Radiocaine™, a new investigational PET radiotracer that targets sodium channels in peripheral nerves. The study aims to determine how safe this radiotracer is when given to healthy adults, as well as how it travels and behaves in the body. The findings will help develop Radiocaine™ as a potential tool for imaging pain in people with chronic or neuropathic pain. This early-stage research is crucial for setting the foundation for future studies involving patients and could lead to better understanding and management of pain. In the study, six healthy adult volunteers will receive a single dose of Radiocaine™ through an intravenous injection. Following the injection, participants will undergo PET/MR imaging over several hours to track where the radiotracer goes in their bodies. Blood and urine samples will also be collected at specific times to help understand how Radiocaine™ is processed by the body. Throughout the study, regular safety checks, including vital signs and lab tests, will be performed to monitor any side effects or adverse reactions. The results will provide valuable insights into the appropriate dosing and timing for future clinical applications.