EPIC-KOPhotobiomodulation and Diclofenac for Knee Osteoarthritis

This study is focused on finding better ways to reduce inflammation and pain in people who have knee osteoarthritis, a common joint condition that can make movement difficult. Researchers are testing two treatments: a light therapy called photobiomodulation (PBM), which uses specific wavelengths of light to help with healing, and a gel containing diclofenac, a medicine often used to treat pain and inflammation. The main goal is to see if using both treatments together is more effective than using just the light therapy alone, which could lead to improved joint function and less pain for those suffering from this condition. Participants in the study will receive either the combined treatment of PBM and diclofenac gel or just the PBM therapy. The PBM therapy involves using a device that emits light directly onto the knee, while the diclofenac is applied as a gel on the skin. Scientists will monitor changes in pain levels, swelling, and how well the knee functions over time. By measuring these outcomes, the study aims to understand the benefits, if any, of combining these treatments, which could provide a new, more effective approach for managing knee osteoarthritis symptoms.