iCHOROSBreztri/Trixeo Outcomes in Moderate to Severe COPD
Data Collection
Collected from today forward - ProspectiveChronic Disease+5
+ Lung Diseases
+ Lung Diseases, Obstructive
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Summary
Study start date: December 15, 2025
Actual date on which the first participant was enrolled.This study focuses on adults with moderate to severe Chronic Obstructive Pulmonary Disease (COPD) who are being treated with a medication called Breztri/Trixeo. COPD is a serious lung condition that makes it hard to breathe and often gets worse over time, leading to frequent hospital visits and a significant impact on quality of life, especially in countries with fewer healthcare resources. The study aims to gather real-world data on how well Breztri/Trixeo works outside of controlled clinical trials. This will involve understanding its effectiveness, safety, and the patient experience, which is crucial for improving treatment strategies and outcomes for those living with COPD across different parts of the world, including Latin America, Asia, and the Middle East. Participants in the study will use Breztri/Trixeo, which is an inhaler that delivers three medications to help manage COPD symptoms. The study will track changes in participants' health by measuring their scores on the COPD Assessment Test (CAT) after 12 weeks of treatment, with additional checks at 26 and 52 weeks. Other important measures will include the frequency of COPD flare-ups and patient satisfaction with the inhaler. The study will involve routine visits to the doctor, where information such as medical history and medication use will be collected. Doctors will decide on all treatments, ensuring that the study reflects typical real-world medical practice. The study will last for up to 52 weeks for each participant, providing valuable insights into how Breztri/Trixeo performs in everyday use.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.1400 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 30 to 80 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 12 locations
Research Site
Cairo, EgyptResearch Site
Abhā, Saudi ArabiaResearch Site
Riyadh, Saudi Arabia