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Amnioreduction for Pregnant Women with Polyhydramnios

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Urogenital Diseases+1

+ Female Urogenital Diseases and Pregnancy Complications

+ Polyhydramnios

+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: August 2025
See protocol details

Summary

Principal SponsorAssiut University
Study ContactMohamed Fekry, PhD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on understanding how a procedure called amnioreduction can help manage pregnancies complicated by polyhydramnios, which is a condition where there is too much amniotic fluid around the baby. Polyhydramnios can happen in about 2% of pregnancies and can lead to problems like preterm birth or fetal abnormalities. This study is important because managing polyhydramnios can be challenging, especially in severe cases. Amnioreduction is known to reduce the risk of preterm labor, ease the mother's discomfort, and might help prolong the pregnancy, benefiting both the mother and the baby. During the study, participants undergo amnioreduction, which involves removing excess amniotic fluid to relieve symptoms and potentially improve pregnancy outcomes. The study observes and records the gestational age at which the baby is delivered, aiming for a longer pregnancy duration, which is considered beneficial. It also tracks the number of cases where a condition called premature rupture of membranes (PROM) occurs, as reducing this risk can lead to better pregnancy results. By understanding these outcomes, the study aims to provide insights into the benefits and risks of amnioreduction, helping to improve care for those with polyhydramnios.

Official TitleBenefits and Risks of Amnioreduction for Management of Pregnant Women With Polyhydramnios
Principal SponsorAssiut University
Study ContactMohamed Fekry, PhD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

28 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsPolyhydramniosPregnancy Complications

Criteria

2 inclusion criteria required to participate
Pregnant women 20- 38 weeks

Patients with polyhydramnios

4 exclusion criteria prevent from participating
Lethal fetal anomalies

Pre labor rupture of membranes

Placental separation

Chorioamnionitis

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Women's Health Hospital

Asyut, EgyptOpen Women's Health Hospital in Google Maps
Recruiting soonOne Study Center