Suspended

Huel Impact on Inflammation Markers Study

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Study Aim

This study explores how Huel, a nutritionally complete food, affects inflammation markers like C-Reactive protein, neutrophils, TNF-alpha, IL-10, and IL-6 in adults.

What is being tested

Huel

Dietary Supplement
Who is being recruted

Inflammation

+ Pathologic Processes

+ Pathological Conditions, Signs and Symptoms

Over 18 Years
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: February 2025
See protocol details

Summary

Principal SponsorNewcastle University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 1, 2025

Actual date on which the first participant was enrolled.

This study is exploring how Huel, a nutritionally complete food product, affects indicators of inflammation in the digestive system of generally healthy people. The research involves 30 participants and focuses on detecting any changes in nine specific markers that indicate the level of inflammation. This is important for understanding whether consuming Huel can influence inflammation, which is linked to various health conditions and could lead to better dietary recommendations or treatments in the future. Participants will first continue their usual diets for one week while their inflammation markers are measured. Then, they will consume two ready-to-drink Huel products each day, one Hot & Savoury Huel meal, and the rest of their calories from Huel Powder (v3.1) for four weeks. This study measures changes in inflammation markers from the start, after the habitual diet period, and after the Huel consumption period to assess any impact. The process is designed to gather data on how dietary changes might affect inflammation in the body.

Official TitleThe Effect of Huel on Markers of Inflammation
Principal SponsorNewcastle University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

30 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

InflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Criteria

Inclusion Criteria: Generally healthy Aged 18 years and over Non-pregnant, Non-lactating non-smoking Exclusion Criteria: Smoker Pregnant Lactating BMI \>30 Food allergy Disordered eating Disorder which could impact the study outcomes Medications which could impact the study outcomes

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Faculty of Medical Sciences

Newcastle upon Tyne, United KingdomOpen Faculty of Medical Sciences in Google Maps
SuspendedOne Study Center