Cerebrolysin Impact on Early Ischemic Stroke Rehabilitation
This study explores if Cerebrolysin can enhance early rehabilitation in individuals who have experienced ischemic stroke, by observing changes in their upper limb function after 90 days.
Cerebrolysin treatment
+ Standard treatment (including neurorehabilitation) of acute ischemic stroke
Ischemic Stroke+5
+ Brain Diseases
+ Cardiovascular Diseases
Treatment Study
Summary
Study start date: June 13, 2025
Actual date on which the first participant was enrolled.Cerebrolysin is a drug made from pig brain proteins and is used to treat various brain conditions, including strokes. This study aims to see how effective Cerebrolysin is in helping patients recover from moderate to severe strokes, specifically in a hospital setting in Ljubljana. The study hopes to show whether adding Cerebrolysin to the usual care for stroke patients can improve their recovery and reduce their neurological impairments, both when they leave the hospital and 90 days later. Participants in the study will have had a recent stroke and will either receive standard stroke care alone or standard care plus Cerebrolysin. Those receiving Cerebrolysin will be given the drug through an IV infusion daily for 10 days. The researchers will then compare the recovery progress between the two groups to determine if Cerebrolysin provides any additional benefit. This involves looking at how much their neurological symptoms improve by the time they are discharged and after three months. The study ensures that the drug is administered safely, using sterile equipment for each infusion.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.30 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: Being able to perform ARAT test Signed informed consent Both sexes, age not specified Acute ischemic stroke confirmed by imaging NIHSS score 6-12 No prior stroke or disability (mRS 0 before stroke) \- Exclusion Criteria: Not being able to perform ARAT test * Previous stroke or disability (mRS \> 0) * The patient unable to understand instructions
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
UMC Ljubljana - Department of Vascular Neurology and Intensive Neurological Therapy (KOVNINT)
Ljubljana, SloveniaOpen UMC Ljubljana - Department of Vascular Neurology and Intensive Neurological Therapy (KOVNINT) in Google Maps