Cognitive Stimulation Impact on Alzheimer's in Multiple Domains & Contexts
This study investigates the impact of cognitive stimulation on Alzheimer's disease in multiple areas and contexts. It evaluates changes in cognitive functioning using tests like the Mini-Mental State Examination, Alzheimer's Disease Assessment Scale - Cognitive Subscale, Memory Alteration Test, and Frontal Assessment Battery.
Digital intervention
+ Physical/Analogue Intervention
Alzheimer Disease+12
+ Anxiety Disorders
+ Behavior
Treatment Study
Summary
Study start date: September 1, 2025
Actual date on which the first participant was enrolled.This study focuses on older adults in Portugal who have mild to moderate Alzheimer's disease, a common form of dementia that affects memory, thinking, and daily functioning. As Portugal has a significant percentage of its elderly population affected by dementia, this research is crucial. The study aims to explore the effectiveness of cognitive stimulation, a non-drug approach that uses structured activities to improve mental functions such as memory, language, and reasoning. This approach is especially important because, while there is currently no cure for Alzheimer's, cognitive stimulation has shown promising results in enhancing cognition, mood, and quality of life for patients. Participants in the study will engage in different types of cognitive stimulation activities within social care settings. The study will measure the effects of these activities on participants' overall cognitive abilities, mood, and quality of life, with a particular focus on executive functions and memory. It will also consider how the resources available in different care facilities and geographic areas might affect these outcomes. By using reliable assessment tools and considering various contextual factors, the study aims to identify effective ways to implement cognitive stimulation that can be adapted to real-world care environments in Portugal.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.514 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: * Age 65 or older. * Receive care/support services for at least three months. * A diagnosis of probable AD according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition, text revision. * Preserved communication skills. * Native Portuguese speaker. * Total scores between 10 and 26 points on the Mini Mental State Examination. Exclusion Criteria: * Cannot read and write. * Significant sensory or physical limitations. * Acute or chronic illness preventing participation. * Severe communication impairment. * Aggressive or disruptive behaviour. * Recent initiation (within two months) of neuroleptics, antipsychotics, or other psychoactive medications.
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 39 locations
Associação de Desenvolvimento Comunitário do Funchal - Garouta do Calhau
Funchal, PortugalInstituto S. João de Deus Funchal
Funchal, PortugalAssociação Alzheimer Açores
Açores, Portugal