LNBLong-term Efficacy of DCB Treatment with Bail-out BRS in Comparison to BRS Treatment of De-novo Native Coronary Artery Lesions in Young PCI Population

This study is focused on comparing two different treatment strategies for patients with new blockages in the heart's blood vessels. The study looks at using a technique called DCB treatment, which involves a special type of balloon to open blocked arteries, followed by a back-up treatment if needed, and compares it to another method called BRS treatment. The goal is to find out which method is more effective and safer for relatively young patients undergoing a procedure called PCI to improve blood flow to the heart. Understanding which treatment works better can help doctors make better decisions for their patients and potentially lead to better long-term heart health outcomes. Participants in this study will receive either the DCB treatment with a possible additional intervention or the BRS treatment. The study will track important outcomes such as whether the blood vessel remains open, if there are any heart attacks, or if additional procedures are needed within 12 months. Additionally, a smaller subset of participants will undergo detailed imaging to assess changes in the blood vessels over 13 months. The main goal is to measure how well the treatments prevent problems with the heart's blood vessels over time, and researchers will carefully monitor any side effects or complications that may arise.